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647926 InSolution™ Trichostatin A, Streptomyces sp. - Calbiochem

647926
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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₁₇H₂₂N₂O₃

Pricing & Availability

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647926-500UG
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      Plastic ampoule 500 μg
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      Description
      Catalogue Number647926
      Brand Family Calbiochem®
      Synonyms4,6-Dimethyl-7-[p-dimethylaminophenyl]-7-oxahepta-2,4-dienohydroxamic Acid, HDAC Inhibitor IX, TSA
      References
      Product Information
      ATP CompetitiveN
      FormLiquid
      FormulationA 10 mM (500 µg/165 µl) solution of Trichostatin A, Streptomyces sp. (Cat. No. 647925) in DMSO.
      Hill FormulaC₁₇H₂₂N₂O₃
      Chemical formulaC₁₇H₂₂N₂O₃
      Hygroscopic Hygroscopic
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targethistone deactylase
      Primary Target IC<sub>50</sub>73 nM inhibiting IL-2 gene expression in Jurkat cells
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Harmful
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InSolution™ Trichostatin A, Streptomyces sp. - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      InSolution™ Trichostatin A, Streptomyces sp. - Calbiochem Certificates of Analysis

      TitleLot Number
      647926
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-September-2008 RFH
      Synonyms4,6-Dimethyl-7-[p-dimethylaminophenyl]-7-oxahepta-2,4-dienohydroxamic Acid, HDAC Inhibitor IX, TSA
      DescriptionA potent and reversible inhibitor of histone deacetylase. Blocks cell cycle progression at the G1 phase in HeLa cells and induces a 12-fold increase in intracellular levels of gelsolin. Induces reversion of oncogenic ras-tranformed NIH 3T3 cells to a normal morphology. Inhibits IL-2 gene expression (IC50 = 73 nM) in Jurkat cells and shows immunosuppressive activity in a mouse model.
      FormLiquid
      FormulationA 10 mM (500 µg/165 µl) solution of Trichostatin A, Streptomyces sp. (Cat. No. 647925) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₇H₂₂N₂O₃
      Structure formulaStructure formula
      Purity≥98% by HPLC
      Storage -20°C
      Hygroscopic
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Harmful