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504483 Homoquinolinic acid - CAS 490-75-5 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3-Carboxymethylpyridine-2-carboxylic acid, 3-Pyridineacetic acid, 2-carboxy-Homoquinolinate

Primary Target: NMDA receptors
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      490-75-5C₈H₇NO₄
      Description
      OverviewA potent agonist for NMDA receptor with subunit-selectivity of NR2A/B (EC50 = 26 µM) over NR2C (EC50 = 60 µM). Used as a potent neurotoxic agent and for identifying endogenous receptors containing the NR2C subunit.
      Catalogue Number504483
      Brand Family Calbiochem®
      Synonyms3-Carboxymethylpyridine-2-carboxylic acid, 3-Pyridineacetic acid, 2-carboxy-Homoquinolinate
      References
      ReferencesOlverman, H., et al, 1988. Neuroscience. 26, 17.
      Prado de Carvalho, I., et al. 1996. Neurochem. Int. 28, 445.
      Stone, T.W. 1984. Br. J. Pharmacol. 81 175.
      Woodhall, G., et al. 2001. J. Neurophysiol. 86 1644.
      Cebere, A., et al. 2003. Neurochem. Res. 28 1193.
      Product Information
      CAS number490-75-5
      FormWhite solid
      Hill FormulaC₈H₇NO₄
      Chemical formulaC₈H₇NO₄
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetNMDA receptors
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Homoquinolinic acid - CAS 490-75-5 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Olverman, H., et al, 1988. Neuroscience. 26, 17.
      Prado de Carvalho, I., et al. 1996. Neurochem. Int. 28, 445.
      Stone, T.W. 1984. Br. J. Pharmacol. 81 175.
      Woodhall, G., et al. 2001. J. Neurophysiol. 86 1644.
      Cebere, A., et al. 2003. Neurochem. Res. 28 1193.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-July-2013 JSW
      Synonyms3-Carboxymethylpyridine-2-carboxylic acid, 3-Pyridineacetic acid, 2-carboxy-Homoquinolinate
      DescriptionA potent agonist for NMDA receptor with subunit-selectivity of NR2A/B (EC50 = 26 µM) over NR2C (EC50 = 60 µM). Used as a potent neurotoxic agent and for identifying endogenous receptors containing the NR2C subunit.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number490-75-5
      Chemical formulaC₈H₇NO₄
      Structure formulaStructure formula
      Purity≥98% by TLC
      Solubility1N NaOH
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesOlverman, H., et al, 1988. Neuroscience. 26, 17.
      Prado de Carvalho, I., et al. 1996. Neurochem. Int. 28, 445.
      Stone, T.W. 1984. Br. J. Pharmacol. 81 175.
      Woodhall, G., et al. 2001. J. Neurophysiol. 86 1644.
      Cebere, A., et al. 2003. Neurochem. Res. 28 1193.