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505313 Hexamethonium Bromide - CAS 55-97-0 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Hexane-1,6-bis(trimethylammonium bromide), Nicotinic Acetylcholine Receptors (nAChRs) Antagonist, Hexamethonium Bromide

Primary Target: nAChR
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      55-97-0C₁₂H₃₀Br₂N₂
      Description
      OverviewA potent antagonist of nicotinic acetylcholine receptors (nAChRs) at pre-ganglionic sites in both the sympathetic and parasympathetic nervous systems. Often used for studying the roles of nicotinic receptors in regulating cardiovascular system.
      Catalogue Number505313
      Brand Family Calbiochem®
      SynonymsHexane-1,6-bis(trimethylammonium bromide), Nicotinic Acetylcholine Receptors (nAChRs) Antagonist, Hexamethonium Bromide
      References
      ReferencesDasgupta, X., et al., 2010. Proc. Natl. Acad. Sci. 103, 6332.Neurosci. Behav. Physiol. 38, 297.
      Nelson, E., 1999. J. Physiol. 516, 657.
      Christ, D. 1980. Br. J. Pharmacol. 69, 249.
      Product Information
      CAS number55-97-0
      FormWhite powder
      Hill FormulaC₁₂H₃₀Br₂N₂
      Chemical formulaC₁₂H₃₀Br₂N₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetnAChR
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Identification Number
      Catalog Number GTIN
      505313

      Documentation

      Hexamethonium Bromide - CAS 55-97-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Dasgupta, X., et al., 2010. Proc. Natl. Acad. Sci. 103, 6332.Neurosci. Behav. Physiol. 38, 297.
      Nelson, E., 1999. J. Physiol. 516, 657.
      Christ, D. 1980. Br. J. Pharmacol. 69, 249.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-July-2013 JSW
      SynonymsHexane-1,6-bis(trimethylammonium bromide), Nicotinic Acetylcholine Receptors (nAChRs) Antagonist, Hexamethonium Bromide
      DescriptionA potent antagonist of nicotinic acetylcholine receptors (nAChRs) at pre-ganglionic sites in both the sympathetic and parasympathetic nervous systems. Often used for studying the roles of nicotinic receptors in regulating cardiovascular system.
      FormWhite powder
      CAS number55-97-0
      Chemical formulaC₁₂H₃₀Br₂N₂
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityH₂O (100 mg/ml)
      Storage Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesDasgupta, X., et al., 2010. Proc. Natl. Acad. Sci. 103, 6332.Neurosci. Behav. Physiol. 38, 297.
      Nelson, E., 1999. J. Physiol. 516, 657.
      Christ, D. 1980. Br. J. Pharmacol. 69, 249.