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324745 Elastase Inhibitor III - Calbiochem

324745
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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₂₂H₃₅ClN₄O₇

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324745-5MG
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      Plastic ampoule 5 mg
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      Description
      OverviewA potent irreversible inhibitor of human leukocyte elastase (HLE)(Ki = 10 µM). Protects against lung injury induced by instillation of elastase.
      Catalogue Number324745
      Brand Family Calbiochem®
      SynonymsHLE Inhibitor, MeOSuc-AAPV-CMK
      References
      ReferencesFletcher, D.S., et al. 1990. Am. Rev. Respir. Dis. 141, 672.
      Stein, R.L., and Trainor, D.A. 1986. Biochemistry 25, 5414.
      Powers, J.C., et al. 1977. Biochim. Biophys. Acta 485, 15.
      Product Information
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₂H₃₅ClN₄O₇
      Chemical formulaC₂₂H₃₅ClN₄O₇
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetHuman leukocyte elastase (HLE)
      Primary Target K<sub>i</sub>10 µM against human leukocyte elastase (HLE)
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-CMK
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Elastase Inhibitor III - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Elastase Inhibitor III - Calbiochem Certificates of Analysis

      TitleLot Number
      324745

      References

      Reference overview
      Fletcher, D.S., et al. 1990. Am. Rev. Respir. Dis. 141, 672.
      Stein, R.L., and Trainor, D.A. 1986. Biochemistry 25, 5414.
      Powers, J.C., et al. 1977. Biochim. Biophys. Acta 485, 15.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-October-2007 RFH
      SynonymsHLE Inhibitor, MeOSuc-AAPV-CMK
      DescriptionA potent inhibitor of human leukocyte elastase (HLE) (Ki = 10 µM).
      FormWhite solid
      Chemical formulaC₂₂H₃₅ClN₄O₇
      Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-CMK
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (10 mg/ml) or Methanol
      Storage -20°C
      Protect from moisture
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesFletcher, D.S., et al. 1990. Am. Rev. Respir. Dis. 141, 672.
      Stein, R.L., and Trainor, D.A. 1986. Biochemistry 25, 5414.
      Powers, J.C., et al. 1977. Biochim. Biophys. Acta 485, 15.

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Elastase Inhibitors
      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors