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505026 DNQX Disodium Salt - CAS 2379-57-9 - Calbiochem

505026
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Key Specifications Table

Empirical FormulaCAS #
C₈H₂N₄O₆Na₂ 2379-57-9

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      Glass bottle 10 mg
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      Description
      OverviewA potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66 µM and 0.35 µM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate and NMDA receptors in studying brain functions and disorders.
      Catalogue Number505026
      Brand Family Calbiochem®
      SynonymsAMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX
      References
      ReferencesLee, S., et al. 2010. J. Neurophysiol. 103, 1728.
      Honor, T., et al. 1998. Science. 241, 701.
      Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
      Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.
      Product Information
      CAS number2379-57-9
      FormDark brown solid
      Hill FormulaC₈H₂N₄O₆Na₂
      Chemical formulaC₈H₂N₄O₆Na₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAMPA
      Primary Target IC<sub>50</sub>0.19 to 1.66 uM
      Secondary targetGluK2
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      DNQX Disodium Salt - CAS 2379-57-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Lee, S., et al. 2010. J. Neurophysiol. 103, 1728.
      Honor, T., et al. 1998. Science. 241, 701.
      Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
      Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-July-2013 JSW
      SynonymsAMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX
      DescriptionA potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66 µM and 0.35 µM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate and NMDA receptors in studying brain functions and disorders.
      FormDark brown solid
      CAS number2379-57-9
      Chemical formulaC₈H₂N₄O₆Na₂
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityH₂O (100 mM)
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesLee, S., et al. 2010. J. Neurophysiol. 103, 1728.
      Honor, T., et al. 1998. Science. 241, 701.
      Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
      Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.