Product Information
Applications
Biological Information
Primary TargetNMDA receptors
Primary Target IC<sub>50</sub>0.039 µM for NR2B and >100 µM for NR2A, NR2C, and NR2D
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

CP-101,606 - CAS 134234-12-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Taniguchi, K., et al. 2009. British J. Pharmacol. 122, 809.
Menniti, F., et al. 1997. Eur. J. Pharmacol. 331, 117.
Nicholson, K., et al. 2007. Behavioural Pharmacology 18, 731.
Bullock, M., et al. 2006. Annals of the New York Academy of Sciences 890, 51.
Preskorn, S., et al. 2008. J. Clin. Psychopharmacol. 28, 631.
Yurkewicz, L., et al. 2005. J. Neurotrauma. 22, 1428.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-June-2013 JSW
SynonymsNMDA Antagonist VI, Traxoprodil, CP-101606, (1S,2S)-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol
DescriptionA highly selective antagonist for NR2B subunit containing NMDA receptors (IC50 = 0.039 µM for NR2B and >100 µM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research.
FormWhite powder
CAS number134234-12-1
Chemical formulaC₂₀H₂₅NO₃
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (35 mg/ml)
Storage +2°C to +8°C
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesTaniguchi, K., et al. 2009. British J. Pharmacol. 122, 809.
Menniti, F., et al. 1997. Eur. J. Pharmacol. 331, 117.
Nicholson, K., et al. 2007. Behavioural Pharmacology 18, 731.
Bullock, M., et al. 2006. Annals of the New York Academy of Sciences 890, 51.
Preskorn, S., et al. 2008. J. Clin. Psychopharmacol. 28, 631.
Yurkewicz, L., et al. 2005. J. Neurotrauma. 22, 1428.

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Categories

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Neurochemicals > Antagonists > Glutamate Receptor Antagonists