504761 CL316243 Hydrate - CAS 138908-40-4 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate

Primary Target: →₃ adrenoceptors
504761
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₁₈ClNNa₂O₇ • H₂O 138908-40-4

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      5.04761.0001
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          		 Glass bottle 5 mg
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          Description
          OverviewA very potent agonist highly selective for β3 adrenoceptors (EC50 = 3 nM). Widely used to assess the functional roles of β3 adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation.
          Catalogue Number504761
          Brand Family Calbiochem®
          SynonymsDisodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate
          References
          ReferencesFlach, R., et al. 2013. Am. J. Pathol. 182, 886.
          Ghorbani, M., et al. 2012. PloS One 7.10, e45874.
          Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077.
          Yoshida, T., et al. 1994. Life Sci. 54, 491.
          Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.
          Product Information
          CAS number138908-40-4
          FormLight beige powder
          Hill FormulaC₂₀H₁₈ClNNa₂O₇ • H₂O
          Chemical formulaC₂₀H₁₈ClNNa₂O₇ • H₂O
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary Target→₃ adrenoceptors
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          References

          Reference overview
          Flach, R., et al. 2013. Am. J. Pathol. 182, 886.
          Ghorbani, M., et al. 2012. PloS One 7.10, e45874.
          Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077.
          Yoshida, T., et al. 1994. Life Sci. 54, 491.
          Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision31-May-2013 JSW
          SynonymsDisodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate
          DescriptionA very potent agonist highly selective for ?3 adrenoceptors (EC50 = 3 nM). Widely used to assess the functional roles of ?3 adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation.
          FormLight beige powder
          CAS number138908-40-4
          Chemical formulaC₂₀H₁₈ClNNa₂O₇ • H₂O
          Structure formulaStructure formula
          Purity≥98% by HPLC
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Toxicity Standard Handling
          ReferencesFlach, R., et al. 2013. Am. J. Pathol. 182, 886.
          Ghorbani, M., et al. 2012. PloS One 7.10, e45874.
          Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077.
          Yoshida, T., et al. 1994. Life Sci. 54, 491.
          Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.