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504795 BRL 44408 Maleate - CAS 118343-19-4 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate

Primary Target: →2A-adrenoceptor
504795
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
118343-19-4C₁₃H₁₇N₃ • C₄H₄O₄

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      Description
      OverviewA selective α2A-adrenoceptor antagonist (Ki = 1.7 nM and 144.5 nM at α2A and α2B-adrenergic receptors respectively). Has been used to study regulation of neurotransmitter release from sympathetic nerves and shown to increase hippocampal noradrenaline release following systemic administration.
      Catalogue Number504795
      Brand Family Calbiochem®
      Synonyms2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate
      References
      ReferencesAlberts, P., et al. 1993. General Pharmacology 24, 1.
      Imaki, J., et al. 2009. Neuroscience Letters 454, 143.
      Carlos, M., et al. 2012. Eur. J. Pharmacol. 683, 204.
      Product Information
      CAS number118343-19-4
      FormTan powder
      Hill FormulaC₁₃H₁₇N₃ • C₄H₄O₄
      Chemical formulaC₁₃H₁₇N₃ • C₄H₄O₄
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target→2A-adrenoceptor
      Primary Target K<sub>i</sub>1.7 nM and 144.5 nM at →2A and →2B-adrenergic receptors respectively
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      BRL 44408 Maleate - CAS 118343-19-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Alberts, P., et al. 1993. General Pharmacology 24, 1.
      Imaki, J., et al. 2009. Neuroscience Letters 454, 143.
      Carlos, M., et al. 2012. Eur. J. Pharmacol. 683, 204.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-July-2013 JSW
      Synonyms2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate
      DescriptionA selective ?2A-adrenoceptor antagonist (Ki = 1.7 nM and 144.5 nM at ?2A and ?2B-adrenergic receptors respectively). Has been used to study regulation of neurotransmitter release from sympathetic nerves and shown to increase hippocampal noradrenaline release following systemic administration.
      FormTan powder
      CAS number118343-19-4
      Chemical formulaC₁₃H₁₇N₃ • C₄H₄O₄
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (10 mg/ml)
      Storage Protect from moisture
      Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesAlberts, P., et al. 1993. General Pharmacology 24, 1.
      Imaki, J., et al. 2009. Neuroscience Letters 454, 143.
      Carlos, M., et al. 2012. Eur. J. Pharmacol. 683, 204.