Millipore Sigma Vibrant Logo

07-412 Anti-dimethyl-Arginine Antibody, symmetric (SYM10)

View Products on
200 µL  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
Request Pricing
Limited Availability
Limited Availability
Limited Quantities Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers


      Contact Customer Service


      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MICC, IP, WBRbSerumPolyclonal Antibody
      Catalogue Number07-412
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-dimethyl-Arginine Antibody, symmetric (SYM10)
      OverviewDoes not recognize non-methylated peptides, peptides containing asymmetrically dimethylated arginines, or a peptide containing a single symmetric dimethylarginine.
      Background InformationArginine methylation is a post-translational modification that results in the formation of asymmetrical and symmetrical dimethylated arginines (a- and sDMA).
      Product Information
      • Positive Control Included: Jurkat cell lysate (12-303)
      PresentationWhole rabbit antiserum containing 0.05% sodium azide and 30% glycerol. Liquid at -20°C.
      Quality LevelMQ100
      ApplicationAnti-dimethyl-Arginine Antibody, symmetric (SYM10) is a high quality Rabbit Polyclonal Antibody for the detection of dimethyl-Arginine & has been validated in ICC, IP & WB.
      Key Applications
      • Immunocytochemistry
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      Immunogenpeptide containing four symmetrical dimethyl-arginine-glycine repeats
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityRecognizes proteins that contain multiple symmetrically dimethylated arginines, including p80-Coilin and the Sm protein B, B' and D.
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      • Methylation
      Molecular Weightvaries
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot in RIPA lysates from Jurkat cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Global Trade Item Number
      Catalog Number GTIN
      07-412 04053252369377


      Anti-dimethyl-Arginine Antibody, symmetric (SYM10) SDS


      Safety Data Sheet (SDS) 

      Anti-dimethyl-Arginine Antibody, symmetric (SYM10) Certificates of Analysis

      TitleLot Number
      Anti-dimethyl-Arginine, symmetric (SYM10) 2484182
      Anti-dimethyl-Arginine, symmetric (SYM10) 2872456
      Anti-dimethyl-Arginine, symmetric (SYM10) (rabbit antiserum) - 2392300 2392300
      Anti-dimethyl-Arginine, symmetric (SYM10) (rabbit antiserum) - 2464585 2464585
      Anti-dimethyl-Arginine, symmetric (SYM10) -3166544 3166544
      Anti-dimethyl-Arginine, symmetric (SYM10) (rabbit antiserum) 2970663
      Anti-dimethyl-Arginine, symmetric (SYM10) (rabbit antiserum) 3082512
      Anti-dimethyl-Arginine, symmetric (SYM10) (rabbit antiserum) 2890843
      Anti-dimethyl-Arginine, symmetric (SYM10) (rabbit antiserum) - 2000854 2000854
      Anti-dimethyl-Arginine, symmetric (SYM10) (rabbit antiserum) - 2032304 2032304


      Reference overviewApplicationPub Med ID
      JMJD6 regulates ERα methylation on arginine.
      Poulard, C; Rambaud, J; Hussein, N; Corbo, L; Le Romancer, M
      PloS one  9  e87982  2014

      Show Abstract
      24498420 24498420
      5-Hydroxymethylcytosine Plays a Critical Role in Glioblastomagenesis by Recruiting the CHTOP-Methylosome Complex.
      Takai, H; Masuda, K; Sato, T; Sakaguchi, Y; Suzuki, T; Suzuki, T; Koyama-Nasu, R; Nasu-Nishimura, Y; Katou, Y; Ogawa, H; Morishita, Y; Kozuka-Hata, H; Oyama, M; Todo, T; Ino, Y; Mukasa, A; Saito, N; Toyoshima, C; Shirahige, K; Akiyama, T
      Cell reports  9  48-60  2014

      Show Abstract
      25284789 25284789
      Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation.
      Kanade, SR; Eckert, RL
      The Journal of biological chemistry  287  7313-23  2012

      Show Abstract
      22199349 22199349
      Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing.
      Deng, X; Gu, L; Liu, C; Lu, T; Lu, F; Lu, Z; Cui, P; Pei, Y; Wang, B; Hu, S; Cao, X
      Proceedings of the National Academy of Sciences of the United States of America  107  19114-9  2010

      Show Abstract
      Western Blotting20956294 20956294
      Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.
      Kowenz-Leutz, E; Pless, O; Dittmar, G; Knoblich, M; Leutz, A
      The EMBO journal  29  1105-15  2010

      Show Abstract
      Immunoprecipitation20111005 20111005
      Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.
      Vagin, VV; Wohlschlegel, J; Qu, J; Jonsson, Z; Huang, X; Chuma, S; Girard, A; Sachidanandam, R; Hannon, GJ; Aravin, AA
      Genes & development  23  1749-62  2009

      Show Abstract Full Text Article
      Immunoprecipitation19584108 19584108
      A proteomic analysis of arginine methylated protein complexes
      Boisvert, F. M., et al
      Mol Cell Proteomics, 2:1319-30 (2003)  2003

      Immunoblotting (Western)14534352 14534352
      Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing.
      Boisvert, Francois-Michel, et al.
      J. Cell Biol., 159: 957-69 (2002)  2002

      Show Abstract
      12486110 12486110

      Related Products & Applications

      Included Positive Control

      Catalog Number Description  
      12-303 Jurkat Cell Lysate Show Pricing & Availability


      Life Science Research > Antibodies and Assays > Primary Antibodies