AB5573-200UL Anti-Urotensin II Receptor Antibody

AB5573-200UL
200 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R WB Rb Affinity Purified Polyclonal Antibody
      Description
      Catalogue NumberAB5573-200UL
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Urotensin II Receptor Antibody
      Alternate Names
      • UTIIR
      • UR2R
      • G Protein Coupled Receptor 14
      References
      Product Information
      FormatAffinity Purified
      Control
      • Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
      PresentationAffinity purified immunoglobulin. Lyophilized from PBS, pH 7.4, containing 1% BSA, 5% sucrose and 0.05% sodium azide. Reconstitute with 200 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min).
      Quality LevelMQ100
      Applications
      ApplicationAnti-Urotensin II Receptor Antibody detects level of Urotensin II Receptor & has been published & validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern blotting: 1:200 using ECL on rat kidney membranes.Dilutions should be made using a carrier protein such as BSA (1-3%). See protocol.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenHighly purified peptide corresponding to residues 154-167 of rat UTIIR (Accession P49684).
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Urotensin II Receptor (UTIIR, UR2U). The epitope specific for Urotensin II Receptor is not present in any other known proteins.

      The immunogen sequence is identical in bovine and conserved in canine (13/14) and human (13/14). Reactivity with other species has not yet been tested.
      Species Reactivity
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • UTS2R
      • UR-II-R
      • UTR
      • UTR2
      • GPR14
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q9UKP6 # High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
      SIZE: 389 amino acids; 42130 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Most abundant expression in the heart and pancreas.
      SIMILARITY: SwissProt: Q9UKP6 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain lyophilized material at -20°C for up to 6 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation