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ST1681 Anti-SIGIRR Mouse mAb (3H8-2G3)

ST1681
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Overview

Replacement Information

Key Specifications Table

Species ReactivityHostAntibody Type
H M Monoclonal Antibody

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ST1681-200UL
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      200 ul
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      Description
      OverviewRecognizes the ~32 kDa SIGIRR protein in HepG2 cells.
      Catalogue NumberST1681
      Brand Family Calbiochem®
      SynonymsAnti-Single Immunoglobulin and Toll-Interleukin 1 Receptor Domain
      References
      Product Information
      FormLiquid
      FormulationUndiluted ascites
      Positive controlHepG2 cells
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (1-5 µg/ml)
      Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      ImmunogenFull-length, recombinant, human SIGIRR (aa 1-411), expressed as a GST fusion protein
      Clone3H8-2G3
      HostMouse
      IsotypeIgM
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Regulatory Review
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-SIGIRR Mouse mAb (3H8-2G3) SDS

      Title

      Safety Data Sheet (SDS) 

      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-November-2010 RFH
      SynonymsAnti-Single Immunoglobulin and Toll-Interleukin 1 Receptor Domain
      ApplicationImmunoblotting (1-5 µg/ml)
      DescriptionMouse monoclonal antibody supplied as ascites. Recognizes the ~32 kDa SIGIRR protein.
      BackgroundThe SIGIRR protein acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. It attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Its extracellular domain is known to interfere with the heterodimerization of Il1R1 and IL1RAP.
      HostMouse
      ImmunogenFull-length, recombinant, human SIGIRR (aa 1-411), expressed as a GST fusion protein
      Clone3H8-2G3
      IsotypeIgM
      Specieshuman
      Positive controlHepG2 cells
      FormLiquid
      FormulationUndiluted ascites
      PreservativeNone
      CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Storage -20°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Regulatory Review