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504394 AIDA - CAS 168560-79-0 - Calbiochem

AIDA - CAS 168560-79-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (RS)-1-Aminoindan-1,5-dicarboxylic acid, UPF 523

Primary Target: mGlu1a
504394
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
168560-79-0C₁₁H₁₁NO₄

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      Description
      OverviewA relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo.
      Catalogue Number504394
      Brand Family Calbiochem®
      Synonyms(RS)-1-Aminoindan-1,5-dicarboxylic acid, UPF 523
      References
      ReferencesPellicciari, R., et al. 1995. J. Med. Chem. 38, 3717.
      Moroni, F., et al. 1997. J. Pharmacol. Exp. Ther. 281, 721.
      Nielsen, K., et al. 1997. Eur. J. Pharmacol. 326, 105.
      Christoffersen, G., et al. 1999, Neuropharmacology. 38, 817.
      Product Information
      CAS number168560-79-0
      FormOff-white powder
      Hill FormulaC₁₁H₁₁NO₄
      Chemical formulaC₁₁H₁₁NO₄
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetmGlu1a
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      References

      Reference overview
      Pellicciari, R., et al. 1995. J. Med. Chem. 38, 3717.
      Moroni, F., et al. 1997. J. Pharmacol. Exp. Ther. 281, 721.
      Nielsen, K., et al. 1997. Eur. J. Pharmacol. 326, 105.
      Christoffersen, G., et al. 1999, Neuropharmacology. 38, 817.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-June-2013 JSW
      Synonyms(RS)-1-Aminoindan-1,5-dicarboxylic acid, UPF 523
      DescriptionAA relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo.
      FormOff-white powder
      CAS number168560-79-0
      Chemical formulaC₁₁H₁₁NO₄
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (2 mg/ml)
      Storage Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesPellicciari, R., et al. 1995. J. Med. Chem. 38, 3717.
      Moroni, F., et al. 1997. J. Pharmacol. Exp. Ther. 281, 721.
      Nielsen, K., et al. 1997. Eur. J. Pharmacol. 326, 105.
      Christoffersen, G., et al. 1999, Neuropharmacology. 38, 817.