504472 (2R,4R)-APDC - CAS 169209-63-6 - Calbiochem

(2R,4R)-APDC - CAS 169209-63-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylate, APDC

Primary Target: mGlu₂ and mGlu₃
504472
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₆H₁₀N₂O₄ 169209-63-6

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      5.04472.0001
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          		 Glass bottle 1 mg
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          Description
          OverviewA highly selective and potent agonist for group II metabotropic glutamate receptor (EC50 = 0.4, 0.4, > 100, > 100, > 300 and > 300 µM for human mGlu2, mGlu3, mGlu1, mGlu5, mGlu4 and mGlu7 receptors respectively). Used as anti- and pro-convulsant, neuroprotectant, antinociceptive, and addiction treatment.
          Catalogue Number504472
          Brand Family Calbiochem®
          Synonyms(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylate, APDC
          References
          ReferencesFolbergrová, J., et al. 2005. Experimental Neurology. 192, 420.
          Fisher, K., et al. 2002. Pharmacol. Bioche. and Behav. 73, 411.
          Schoepp, D., et al. 1995. Neuropharmacology. 34, 843.
          Monn, J., et al. 1996. J. Med. Chem. 39, 2990.
          Product Information
          CAS number169209-63-6
          FormOff-white powder
          Hill FormulaC₆H₁₀N₂O₄
          Chemical formulaC₆H₁₀N₂O₄
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetmGlu₂ and mGlu₃
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          (2R,4R)-APDC - CAS 169209-63-6 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Folbergrová, J., et al. 2005. Experimental Neurology. 192, 420.
          Fisher, K., et al. 2002. Pharmacol. Bioche. and Behav. 73, 411.
          Schoepp, D., et al. 1995. Neuropharmacology. 34, 843.
          Monn, J., et al. 1996. J. Med. Chem. 39, 2990.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-August-2017 JSW
          Synonyms(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylate, APDC
          DescriptionA highly selective and potent agonist for group II metabotropic glutamate receptor (EC50 = 0.4, 0.4, > 100, > 100, > 300 and > 300 µM for human mGlu2, mGlu3, mGlu1, mGlu5, mGlu4 and mGlu7 receptors respectively). Used as anti- and pro-convulsant, neuroprotectant, antinociceptive, and addiction treatment.
          FormOff-white powder
          CAS number169209-63-6
          Chemical formulaC₆H₁₀N₂O₄
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (100 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesFolbergrová, J., et al. 2005. Experimental Neurology. 192, 420.
          Fisher, K., et al. 2002. Pharmacol. Bioche. and Behav. 73, 411.
          Schoepp, D., et al. 1995. Neuropharmacology. 34, 843.
          Monn, J., et al. 1996. J. Med. Chem. 39, 2990.