505419 α,β-methylene ATP - CAS 104809-20-3 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: αβ-MeATP, αβ-methylene ATP, P2X purinergic receptor agonist, α,β-methylene ATP, α,β-Methyleneadenosine 5ʹ-triphosphate lithium salt

Primary Target: P2X
505419
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₁H₁₈N₅O₁₂P₃ • xLi+ 104809-20-3

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      5.05419.0001
      Retrieving availability...
      —
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Glass bottle 5 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          Description
          OverviewA metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (~1 mM). Shown to depolarize cells of the longitudinal muscle strips (~ 200 nM to 4 µM) that reaches a peak within 2-3 min after application and then decays to a steady level.
          Catalogue Number505419
          Brand Family Calbiochem®
          Synonymsαβ-MeATP, αβ-methylene ATP, P2X purinergic receptor agonist, α,β-methylene ATP, α,β-Methyleneadenosine 5ʹ-triphosphate lithium salt
          References
          ReferencesSawyer, G.W., et al. 2000. Br. J. Pharmacol. 129, 1458.
          Komori, S., et al. 1988. Br. J. Pharmacol. 94, 9.
          Product Information
          CAS number104809-20-3
          FormWhite powder
          Hill FormulaC₁₁H₁₈N₅O₁₂P₃ • xLi+
          Chemical formulaC₁₁H₁₈N₅O₁₂P₃ • xLi+
          Hygroscopic Hygroscopic
          ReversibleY
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetP2X
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          α,β-methylene ATP - CAS 104809-20-3 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Sawyer, G.W., et al. 2000. Br. J. Pharmacol. 129, 1458.
          Komori, S., et al. 1988. Br. J. Pharmacol. 94, 9.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-August-2013 JSW
          Synonymsαβ-MeATP, αβ-methylene ATP, P2X purinergic receptor agonist, α,β-methylene ATP, α,β-Methyleneadenosine 5ʹ-triphosphate lithium salt
          DescriptionA metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (~1 mM). Shown to depolarize cells of the longitudinal muscle strips (~ 200 nM to 4 µM) that reaches a peak within 2-3 min after application and then decays to a steady level.
          FormWhite powder
          CAS number104809-20-3
          Chemical formulaC₁₁H₁₈N₅O₁₂P₃ • xLi+
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (100 mg/ml)
          Storage -20°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesSawyer, G.W., et al. 2000. Br. J. Pharmacol. 129, 1458.
          Komori, S., et al. 1988. Br. J. Pharmacol. 94, 9.