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505762 (+/-)-Clopidogrel Hydrogensulfate - CAS 135046-48-9 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Purinergic P2Y12 Receptor Antagonist, (+/-)-Clopidogrel, Plavix

Primary Target: P2Y₁₂
505762
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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₁₆H₁₆ClNO₂S•H₂SO₄

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      Description
      OverviewA thienopyridine compound that acts as a specific irreversible inhibitor of purinergic P2Y12 receptors. Blocks ADP-induced platelet aggregation and serves as an anti-thrombotic agent. Shown to reduce vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. Clopidogrel is a prodrug that requires activation by CYP enzyme system to produce its pharmacologically active metabolite.
      Catalogue Number505762
      Brand Family Calbiochem®
      SynonymsPurinergic P2Y12 Receptor Antagonist, (+/-)-Clopidogrel, Plavix
      References
      ReferencesLiu, O., et al. 2012. PLoS One. 7, e51707.
      Savi, P., et al. 2005. Semin. Thromb. Hemost. 31, 174.
      Product Information
      CAS number135046-48-9
      FormWhite powder
      Hill FormulaC₁₆H₁₆ClNO₂S•H₂SO₄
      Chemical formulaC₁₆H₁₆ClNO₂S•H₂SO₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetP2Y₁₂
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      (+/-)-Clopidogrel Hydrogensulfate - CAS 135046-48-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Liu, O., et al. 2012. PLoS One. 7, e51707.
      Savi, P., et al. 2005. Semin. Thromb. Hemost. 31, 174.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-August-2013 JSW
      SynonymsPurinergic P2Y12 Receptor Antagonist, (+/-)-Clopidogrel, Plavix
      DescriptionA thienopyridine compound that acts as a specific irreversible inhibitor of purinergic P2Y12 receptors. Blocks ADP-induced platelet aggregation and serves as an anti-thrombotic agent. Shown to reduce vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. Clopidogrel is a prodrug that requires activation by CYP enzyme system to produce its pharmacologically active metabolite.
      FormWhite powder
      CAS number135046-48-9
      Chemical formulaC₁₆H₁₆ClNO₂S•H₂SO₄
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (25 mg/ml)
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesLiu, O., et al. 2012. PLoS One. 7, e51707.
      Savi, P., et al. 2005. Semin. Thromb. Hemost. 31, 174.