Proteomic analysis requires depletion of overrepresented species to detect rarer biomarkers. Using albumin-binding resin with the Amicon® Pro system provides the perfect tool for rapid sample depletion. Following resin binding, attach the Amicon® Ultra filter prior to centrifugal passage of the unbound fraction for simultaneous sample depletion with concentration in one step.
Depletion-Enrichment Protocol
Complete IgG Depletion from Rabbit Serum Using Amicon® Pro (left) and Traditional (right) Depletion Methods