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PyOxim – A New Coupling Reagent for SPPS

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PyOxim is a new, cost-effective coupling reagent that combines the advantages of Oxyma Pure-based reagents with those of phosphonium coupling reagents, making it the ideal choice for both solution and solid phase synthesis.

Features and Benefits

  • Mediates coupling with superior efficiency to PyBOP, TBTU, and HCTU
  • Mediates coupling with low racemization or epimerization
  • Ideal for fragment condensation and synthesis of cyclic peptides as the reagent cannot cause guanidinylation
  • Excellent solubility in DMF and NMP
ProductCatalog number
PyOxim 851095