PyOxim – A New Coupling Reagent for SPPS
PyOxim is a new, cost-effective coupling reagent that combines the advantages of Oxyma Pure-based reagents with those of phosphonium coupling reagents, making it the ideal choice for both solution and solid phase synthesis.
Features and Benefits
- Mediates coupling with superior efficiency to PyBOP, TBTU, and HCTU
- Mediates coupling with low racemization or epimerization
- Ideal for fragment condensation and synthesis of cyclic peptides as the reagent cannot cause guanidinylation
- Excellent solubility in DMF and NMP