Millipore Sigma Vibrant Logo

LiChrospher® 100 RP-18 and RP-18 Endcapped HPLC Columns

Request Information

Reliability Meets Versatility in Reversed-Phase Separations.

Merck:/Freestyle/LE-Lab-Essentials/Chromatography/LE-Chrom-LiChrospher® HPLC columns-150x245-02212014.pngLiChrospher® 100 RP-18 and RP-18 endcapped HPLC columns are very reliable and highly versatile. These traditionally manufactured spherical silica based supports are designed for reversed-phase chromatography of acidic, neutral and weakly basic compounds – substances frequently found in all analytical fields. With LiChrospher® RP-18, several individual batches are used to produce a large master batch of the sorbent. This eliminates variations between different small batches, and ensures the sorbent’s excellent batch-to-batch consistency. Consequently, LiChrospher® RP-18 delivers highly reproducible results, and secures the reliability of your HPLC method.

Features and Benefits

  • Suitable for acidic, neutral and weakly basic compounds
  • Optimal column selectivity and performance
  • Reproducible results due to excellent batch-to-batch consistency Master batch concept for LiChrospher® RP-18 ensures highly reproducible results
  • Enable faster, more accurate method development


LiChrospher® 100 RP-18 and RP-18 endcapped

Application Examples

To view all available applications, please visit our Analytical Application Finder or use the search function.

Pharmaceutical analysis: Acetyl salicylic acid

Pharmaceutical analysis: 2-Oxoacids

Pharmaceutical analysis: Corticoids

Environmental analysis: Naphthols, chlorophenol and nitro aromatics in water

Application Notes Finder
Search for chromatography applications by analyte, column type, detection method, sorbent type or any other search term:
GC Columns

Columns, solvents, standards & CRMs for GC
View our full line of GC products at

Learn more
HPLC Workflow Solutions - Stationary Phase

HPLC Workflow Solutions

Stationary Phase

Learn More