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Description
Overview
A potent antagonist for α2-adrenoceptors (pKi values are 8.52, 8.00 and 9.17 for human α2a, α2B and α2C receptors respectively). Often used as pharmacological stressor in animal studies.
Calu, D., et al. 2013. J. Neurosci.33, 214. Doxey, L., et al. 1984. Naunyn Schmiedebergs Arch. Pharmacol.325, 136. Goldberg, K., et al. 1987. Pharmacol. Rev.35, 143. Lalchandani, et al. 2002. J. Pharmacol. Exp. Ther.303, 979.
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Product Usage Statements
Storage and Shipping Information
Ship Code
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
-20°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°c). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Documentation
Yohimbine Hydrochloride - CAS 65-19-0 - Calbiochem SDS
Calu, D., et al. 2013. J. Neurosci.33, 214. Doxey, L., et al. 1984. Naunyn Schmiedebergs Arch. Pharmacol.325, 136. Goldberg, K., et al. 1987. Pharmacol. Rev.35, 143. Lalchandani, et al. 2002. J. Pharmacol. Exp. Ther.303, 979.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A potent antagonist for α2-adrenoceptors (pKi values are 8.52, 8.00 and 9.17 for human α2a, α2B and α2C receptors respectively). Often used as pharmacological stressor in animal studies.
Form
Pale yellow solid
CAS number
65-19-0
Chemical formula
C₂₁H₂₆N₂O₃ • HCl
Structure formula
Purity
≥98% by HPLC
Solubility
DMSO (25 mM). Slight warming is required for complete solubilization.
Storage
-20°C
Protect from light
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°c). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Toxic
References
Calu, D., et al. 2013. J. Neurosci.33, 214. Doxey, L., et al. 1984. Naunyn Schmiedebergs Arch. Pharmacol.325, 136. Goldberg, K., et al. 1987. Pharmacol. Rev.35, 143. Lalchandani, et al. 2002. J. Pharmacol. Exp. Ther.303, 979.