504777 Yohimbine Hydrochloride - CAS 65-19-0 - Calbiochem

Yohimbine Hydrochloride is a potent antagonist for α₂-adrenoceptors, α2B and α2C receptors respectively).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride, α₂-Adrenoceptor Antagonist, Yohimbine Hydrochloride

Primary Target: →₂-adrenoceptor
504777
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₁H₂₆N₂O₃ • HCl 65-19-0

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      5.04777.0001
      Retrieving availability...
      —
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Glass bottle 1 gm
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          Description
          OverviewA potent antagonist for α2-adrenoceptors (pKi values are 8.52, 8.00 and 9.17 for human α2a, α2B and α2C receptors respectively). Often used as pharmacological stressor in animal studies.
          Catalogue Number504777
          Brand Family Calbiochem®
          Synonyms17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride, α₂-Adrenoceptor Antagonist, Yohimbine Hydrochloride
          References
          ReferencesCalu, D., et al. 2013. J. Neurosci. 33, 214.
          Doxey, L., et al. 1984. Naunyn Schmiedebergs Arch. Pharmacol. 325, 136.
          Goldberg, K., et al. 1987. Pharmacol. Rev. 35, 143.
          Lalchandani, et al. 2002. J. Pharmacol. Exp. Ther. 303, 979.
          Product Information
          CAS number65-19-0
          FormPale yellow solid
          Hill FormulaC₂₁H₂₆N₂O₃ • HCl
          Chemical formulaC₂₁H₂₆N₂O₃ • HCl
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary Target→₂-adrenoceptor
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 25

          Toxic if swallowed.
          S PhraseS: 22-36/37/39-45

          Do not breathe dust.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°c). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Yohimbine Hydrochloride - CAS 65-19-0 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Calu, D., et al. 2013. J. Neurosci. 33, 214.
          Doxey, L., et al. 1984. Naunyn Schmiedebergs Arch. Pharmacol. 325, 136.
          Goldberg, K., et al. 1987. Pharmacol. Rev. 35, 143.
          Lalchandani, et al. 2002. J. Pharmacol. Exp. Ther. 303, 979.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-July-2013 JSW
          Synonyms17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride, α₂-Adrenoceptor Antagonist, Yohimbine Hydrochloride
          DescriptionA potent antagonist for α2-adrenoceptors (pKi values are 8.52, 8.00 and 9.17 for human α2a, α2B and α2C receptors respectively). Often used as pharmacological stressor in animal studies.
          FormPale yellow solid
          CAS number65-19-0
          Chemical formulaC₂₁H₂₆N₂O₃ • HCl
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (25 mM). Slight warming is required for complete solubilization.
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°c). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Toxic
          ReferencesCalu, D., et al. 2013. J. Neurosci. 33, 214.
          Doxey, L., et al. 1984. Naunyn Schmiedebergs Arch. Pharmacol. 325, 136.
          Goldberg, K., et al. 1987. Pharmacol. Rev. 35, 143.
          Lalchandani, et al. 2002. J. Pharmacol. Exp. Ther. 303, 979.