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505816 Xanomeline Oxalate - CAS 141064-23-5 - Calbiochem

Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
141064-23-5C₁₄H₂₃N₃OS•C₂H₂O₄

Products

Catalog NumberPackaging Qty/Pack
5.05816.0001 Glass bottle 10 mg
Description
OverviewAn agonist selective for muscarinic acetylcholine receptor (mAChR) subtype M1 (EC50 = 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). An antipsychotic agent. Used in improving cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia.
Catalogue Number505816
Brand Family Calbiochem®
Synonyms3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole, Muscarinic Acetylcholine Receptor (mAChR) Agonist, Xanomeline
References
ReferencesWang, D., et al., 2011. Biochem. Biophys. Res. Commun. 410, 229.
Si, W., et al., 2010. Neurosci. Lett. 473, 115.
Stanhope, et al., 2001. J. Exp. Pharmacol. Ther. 299, 782.
Product Information
CAS number141064-23-5
FormOff-white solid
Hill FormulaC₁₄H₂₃N₃OS•C₂H₂O₄
Chemical formulaC₁₄H₂₃N₃OS•C₂H₂O₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Identification Number
Catalog Number GTIN
5.05816.00014055977263022

Documentation

Xanomeline Oxalate - CAS 141064-23-5 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Wang, D., et al., 2011. Biochem. Biophys. Res. Commun. 410, 229.
Si, W., et al., 2010. Neurosci. Lett. 473, 115.
Stanhope, et al., 2001. J. Exp. Pharmacol. Ther. 299, 782.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2013 JSW
Synonyms3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole, Muscarinic Acetylcholine Receptor (mAChR) Agonist, Xanomeline
DescriptionAn agonist selective for muscarinic acetylcholine receptor (mAChR) subtype M1 (EC50 = 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). An antipsychotic agent. Used in improving cognitive deficits and behavioral disturbances in Alzheimer′s disease and schizophrenia.
FormOff-white solid
CAS number141064-23-5
Chemical formulaC₁₄H₂₃N₃OS•C₂H₂O₄
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (10 mM) or Ethanol (25 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesWang, D., et al., 2011. Biochem. Biophys. Res. Commun. 410, 229.
Si, W., et al., 2010. Neurosci. Lett. 473, 115.
Stanhope, et al., 2001. J. Exp. Pharmacol. Ther. 299, 782.