12-338 Sigma-AldrichWortmannin, (PI3 Kinase inhibitor)
The Wortmannin, (PI3 Kinase inhibitor) controls the biological activity of PI3 Kinase. This small molecule/inhibitor is primarily used for Biochemicals applications.
More>> The Wortmannin, (PI3 Kinase inhibitor) controls the biological activity of PI3 Kinase. This small molecule/inhibitor is primarily used for Biochemicals applications. Less<<Recommended Products
Overview
Replacement Information |
---|
References |
---|
Product Information | |
---|---|
HS Code | 3822 19 90 |
Presentation | 1mg of lyophilized powder packaged under inert gas. White to off-white powder. |
Quality Level | MQ100 |
Physicochemical Information |
---|
Dimensions |
---|
Materials Information |
---|
Toxicological Information |
---|
Safety Information according to GHS |
---|
Safety Information |
---|
Packaging Information | |
---|---|
Material Size | 1 mg |
Transport Information |
---|
Supplemental Information |
---|
Specifications |
---|
Global Trade Item Number | |
---|---|
Catalog Number | GTIN |
12-338 | 04053252405112 |
Documentation
Wortmannin, (PI3 Kinase inhibitor) SDS
Title |
---|
Wortmannin, (PI3 Kinase inhibitor) Certificates of Analysis
Title | Lot Number |
---|---|
Wortmannin (PI3 Kinase inhibitor) - 2153577 | 2153577 |
Wortmannin (PI3 Kinase inhibitor) - 2375500 | 2375500 |
Wortmannin (PI3 Kinase inhibitor) | 2930507 |
Wortmannin (PI3 Kinase inhibitor) | 2960506 |
Wortmannin (PI3 Kinase inhibitor) | 3098899 |
Wortmannin (PI3 Kinase inhibitor) | 2475643 |
Wortmannin (PI3 Kinase inhibitor) | 2886360 |
Wortmannin (PI3 Kinase inhibitor) - 2202511 | 2202511 |
Wortmannin (PI3 Kinase inhibitor) - 2290358 | 2290358 |
Wortmannin (PI3 Kinase inhibitor) - 2558391 | 2558391 |
References
Reference overview | Application | Pub Med ID |
---|---|---|
Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation Okano, J., et al J Biol Chem, 275:30934-42 (2000) 2000 | Immunoblotting (Western) | 10908564 |
Wortmannin, a specific inhibitor of phosphatidylinositol-3 kinase, blocks osteoclastic bone resorption. Nakamura, I, et al. FEBS Lett., 361: 79-84 (1995) 1995 Show Abstract | 7890044 | |
Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase. Cross, M J, et al. J. Biol. Chem., 270: 25352-5 (1995) 1995 Show Abstract | 7592698 | |
Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Ui, M, et al. Trends Biochem. Sci., 20: 303-7 (1995) 1995 Show Abstract | 7667888 | |
Platelet-derived growth factor-induced phosphatidylinositol 3-kinase activation mediates actin rearrangements in fibroblasts. Wymann, M and Arcaro, A Biochem. J., 298 Pt 3: 517-20 (1994) 1994 Show Abstract | 8141762 | |
Wortmannin inhibits mitogen-activated protein kinase activation induced by platelet-activating factor in guinea pig neutrophils. Ferby, I M, et al. J. Biol. Chem., 269: 30485-8 (1994) 1994 Show Abstract | 7982965 | |
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin Okada, T, et al J Biol Chem, 269:3568-73 (1994) 1994 | 8106400 |
Technical Info
Title |
---|
Unlocking the Mystery of Cancer: Do the Mutant p110α Subunits of PI3-Kinase Hold the Key? |