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108386 Tris(hydroxymethyl)aminomethane

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-86-1201-064-4C₄H₁₁NO₃H₂NC(CH₂OH)₃121.14 g/molPh Eur,BP,ChP,JPC,USP

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
1.08386.1000
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      Plastic bottle 1 kg
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      1083865000
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          Plastic bottle 5 kg
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          1083869025
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              25 kg
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              Description
              Catalogue Number108386
              SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
              DescriptionTris(hydroxymethyl)aminomethane
              References
              Product Information
              CAS number77-86-1
              EC number201-064-4
              GradePh Eur,BP,ChP,JPC,USP
              Hill FormulaC₄H₁₁NO₃
              Chemical formulaH₂NC(CH₂OH)₃
              Molar Mass121.14 g/mol
              HS Code2922 19 00
              Structure formula ImageStructure formula Image
              Quality LevelMQ500
              Applications
              Biological Information
              Physicochemical Information
              Boiling point219 - 220 °C (13.3 hPa)
              Density1.32 g/cm3 (20 °C)
              Melting Point169 °C
              pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
              Vapor pressure<0.1 hPa (20 °C)
              Bulk density840 kg/m3
              Solubility678 g/l
              Dimensions
              Materials Information
              Toxicological Information
              LD 50 oralLD50 Rat > 5000 mg/kg
              LD 50 dermalLD50 Rat > 5000 mg/kg
              Safety Information according to GHS
              RTECSTY2900000
              Storage class10 - 13 Other liquids and solids
              WGKWGK 1 slightly hazardous to water
              Disposal3
              Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              StorageNoTempLimit
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              Material Qualification Dossier

              TitleVersion
              2.0

              Quality Management Dossier

              Title

              Operational Excellence Dossier

              Title

              Tris(hydroxymethyl)aminomethane SDS

              Title

              Safety Data Sheet (SDS) 

              Tris(hydroxymethyl)aminomethane Certificates of Analysis

              Product Number PackagingSpecificationLot Number
              1.08386.1000 Plastic bottlePDF Specification Document
              1083865000 Plastic bottlePDF Specification Document
              1083869025 PDF Specification Document

              Certificates

              Title

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              Categories

              Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
              Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
              Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
              Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers