108386 Tris(hydroxymethyl)aminomethane

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-86-1 201-064-4 C₄H₁₁NO₃ H₂NC(CH₂OH)₃ 121.14 g/mol Ph Eur,BP,ChP,JPC,USP

Pricing & Availability

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1083860003
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      Fibre case 3 x1 kg
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      1.08386.1000
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          Plastic bottle 1 kg
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          1083865000
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              Plastic bottle 5 kg
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              1083869025
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                  Plastic drum 25 kg
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                  Description
                  Catalogue Number108386
                  SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
                  DescriptionTris(hydroxymethyl)aminomethane
                  References
                  Product Information
                  CAS number77-86-1
                  EC number201-064-4
                  GradePh Eur,BP,ChP,JPC,USP
                  Hill FormulaC₄H₁₁NO₃
                  Chemical formulaH₂NC(CH₂OH)₃
                  Molar Mass121.14 g/mol
                  HS Code2922 19 00
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ500
                  Applications
                  Biological Information
                  Physicochemical Information
                  Boiling point219 - 220 °C (13.3 hPa)
                  Density1.35 g/cm3 (23 °C)
                  Melting Point171 - 172 °C
                  pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
                  Vapor pressure0.0267 hPa (20 °C)
                  Bulk density840 kg/m3
                  Solubility678 g/l
                  Dimensions
                  Materials Information
                  Toxicological Information
                  LD 50 oralLD50 Rat > 5000 mg/kg
                  LD 50 dermalLD50 Rat > 5000 mg/kg
                  Safety Information according to GHS
                  RTECSTY2900000
                  Storage class10 - 13 Other liquids and solids
                  WGKWGK 1 slightly hazardous to water
                  Disposal3
                  Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  StorageStorage temperature: no restrictions.
                  Packaging Information
                  Transport Information
                  Supplemental Information
                  Specifications

                  Documentation

                  Material Qualification Dossier

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                  Quality Management Dossier

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                  Operational Excellence Dossier

                  Title

                  Tris(hydroxymethyl)aminomethane SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Tris(hydroxymethyl)aminomethane Certificates of Analysis

                  Product Number PackagingSpecificationLot Number
                  1083860003 Fibre casePDF Specification Document
                  1.08386.1000 Plastic bottlePDF Specification Document
                  1083865000 Plastic bottlePDF Specification Document
                  1083869025 Plastic drumPDF Specification Document

                  Certificates

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                  Categories

                  Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers
                  Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
                  Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
                  Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers