Millipore Sigma Vibrant Logo

574775 Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem

574775
View Pricing & Availability

Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₈H₁₅NO₃ 72741-87-8

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
574775-500UG
Retrieving availability...
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Plastic ampoule 500 μg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      Description
      OverviewReversible active-site inhibitor of lysosomal α-mannosidase. Inhibits the growth of tumors and prevents metastasis in murine models. Blocks the processing of high mannose to complex type oligosaccharides.
      Catalogue Number574775
      Brand Family Calbiochem®
      Synonyms(1S,2S,8R,8aR)-Trihydroxyindolizidine, 8aβ-Indolizidine-1α,2α,8β-triol
      References
      ReferencesMochizuki, H., et al. 1993. J. Biol. Chem. 268, 9143.
      Elbein, A.D. 1983. Methods Enzymol. 98, 135.
      Product Information
      CAS number72741-87-8
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₈H₁₅NO₃
      Chemical formulaC₈H₁₅NO₃
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetLysosomal α-mannosidase
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      574775

      References

      Reference overview
      Mochizuki, H., et al. 1993. J. Biol. Chem. 268, 9143.
      Elbein, A.D. 1983. Methods Enzymol. 98, 135.

      Citations

      Title
    • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      Synonyms(1S,2S,8R,8aR)-Trihydroxyindolizidine, 8aβ-Indolizidine-1α,2α,8β-triol
      DescriptionReversible active-site inhibitor of lysosomal α-mannosidase. Inhibits the growth of tumors and prevents metastasis in murine models. Blocks the processing of high mannose to complex type oligosaccharides.
      FormWhite solid
      CAS number72741-87-8
      Chemical formulaC₈H₁₅NO₃
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (5 mg/ml), H₂O (1 mg/ml), or Chloroform
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Harmful
      ReferencesMochizuki, H., et al. 1993. J. Biol. Chem. 268, 9143.
      Elbein, A.D. 1983. Methods Enzymol. 98, 135.
      Citation
    • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.