505986 SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: GABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531

Primary Target: GABAA
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₅H₁₇N₃O₃•HBr 104104-50-9

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      5.05986.0001
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          		 Glass bottle 10 mg
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          Description
          OverviewA selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 µM). Also shown to block glycine receptors, but with low affinity (Kb = 190 µM).
          Catalogue Number505986
          Brand Family Calbiochem®
          SynonymsGABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
          References
          ReferencesMuroi, Y., et al. 2009. Biophys. J. 96, 499.
          Beato, M., et al. 2007. J. Physiol. 580, 171.
          Uchida, I., et al. 1996. Eur. J. Pharmacol. 307, 89.
          Product Information
          CAS number104104-50-9
          FormWhite solid
          Hill FormulaC₁₅H₁₇N₃O₃•HBr
          Chemical formulaC₁₅H₁₇N₃O₃•HBr
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetGABAA
          Primary Target IC<sub>50</sub>440 nM
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Muroi, Y., et al. 2009. Biophys. J. 96, 499.
          Beato, M., et al. 2007. J. Physiol. 580, 171.
          Uchida, I., et al. 1996. Eur. J. Pharmacol. 307, 89.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision20-September-2013 JSW
          SynonymsGABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
          DescriptionA selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 mM). Also shown to block glycine receptors, but with low affinity (Kb = 190 mM).
          FormWhite solid
          CAS number104104-50-9
          Chemical formulaC₁₅H₁₇N₃O₃•HBr
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (25 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesMuroi, Y., et al. 2009. Biophys. J. 96, 499.
          Beato, M., et al. 2007. J. Physiol. 580, 171.
          Uchida, I., et al. 1996. Eur. J. Pharmacol. 307, 89.