505228 S 24795 - CAS 304679-75-2 - Calbiochem

505228
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Key Specifications Table

Empirical FormulaCAS #
C₁₄H₁₃BrNOI 304679-75-2

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      Glass bottle 10 mg
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      Description
      OverviewA potent partial agonist selective for α7 nAChRs (EC50 = 34 µM). Widely used in investigating the roles of α7 nAChRs in aging, learning and memory, and cognition. Enhances memory in mouse models for Alzheimer′s disease.
      Catalogue Number505228
      Brand Family Calbiochem®
      Synonymsalpha 7 Nicotinic Acetylcholine Receptor Agonist, S 24795, 2-(2-(4-bromophenyl)-2-oxoethyl)-1-methylpyridin-1-ium iodide, alpha 7 nAChR agonist, S 24795, S-24795, S24795
      References
      ReferencesTronche, C., et al., 2010. Behav Brain Res. 215, 255.
      Beracochea, D., et al., 2008. Psychopharmacol. (Berl). 196, 555.
      Lagostena, L., et al., 2008. Neuropharmacol. 54, 676.
      Lopez-Hernandez, G., et al., 2007. Neuropharmacol. 53, 134.
      Product Information
      CAS number304679-75-2
      FormPink solid
      Hill FormulaC₁₄H₁₃BrNOI
      Chemical formulaC₁₄H₁₃BrNOI
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target→7 nAChRs
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      S 24795 - CAS 304679-75-2 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Tronche, C., et al., 2010. Behav Brain Res. 215, 255.
      Beracochea, D., et al., 2008. Psychopharmacol. (Berl). 196, 555.
      Lagostena, L., et al., 2008. Neuropharmacol. 54, 676.
      Lopez-Hernandez, G., et al., 2007. Neuropharmacol. 53, 134.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-July-2013 JSW
      Synonymsalpha 7 Nicotinic Acetylcholine Receptor Agonist, S 24795, 2-(2-(4-bromophenyl)-2-oxoethyl)-1-methylpyridin-1-ium iodide, alpha 7 nAChR agonist, S 24795, S-24795, S24795
      DescriptionA potent partial agonist selective for α7 nAChRs (EC50 = 34 µM). Widely used in investigating the roles of α7 nAChRs in aging, learning and memory, and cognition. Enhances memory in mouse models for Alzheimer′s disease.
      FormPink solid
      CAS number304679-75-2
      Chemical formulaC₁₄H₁₃BrNOI
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (100 mM)
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesTronche, C., et al., 2010. Behav Brain Res. 215, 255.
      Beracochea, D., et al., 2008. Psychopharmacol. (Berl). 196, 555.
      Lagostena, L., et al., 2008. Neuropharmacol. 54, 676.
      Lopez-Hernandez, G., et al., 2007. Neuropharmacol. 53, 134.