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506130 Reserpine - CAS 50-55-5 - Calbiochem

Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
50-55-5C₃₃H₄₀N₂O₉

Products

Catalog NumberPackaging Qty/Pack
5.06130.0001 Glass bottle 250 mg
Description
OverviewBinds the vesicular monoamine transporter (VMAT2) and acts as an irreversible transport inhibitor of biogenic amines. Used as a long-lasting bioamine depleter. Prevents bioamine transport into synaptic vesicles and chromaffin granules. Used as antihypertensive and antipsychotic drugs.
Catalogue Number506130
Brand Family Calbiochem®
SynonymsVMAT2 Inhibitor, Reserpine, Vesicular monoamine transporter (VMAT) Antagonist, Reserpine
References
ReferencesOe, T., et al. 2010. Neurosci. 169, 1860.
Metzger, R. et al. 2002. Eur. J. Pharmacol. 456, 39.
Heslop, E., et al. 1999. Neuropharmacol. 38, 883.
Schuldiner, S., et al. 1993. J. Biol. Chem. 268, 29.
Product Information
CAS number50-55-5
FormOff-white solid
Hill FormulaC₃₃H₄₀N₂O₉
Chemical formulaC₃₃H₄₀N₂O₉
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetVMAT2
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 22

Harmful if swallowed.
S PhraseS: 46

If swallowed, seek medical advice immediately and show this container or label.
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Harmful & Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
5.06130.0001 04055977243123

Documentation

Reserpine - CAS 50-55-5 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Oe, T., et al. 2010. Neurosci. 169, 1860.
Metzger, R. et al. 2002. Eur. J. Pharmacol. 456, 39.
Heslop, E., et al. 1999. Neuropharmacol. 38, 883.
Schuldiner, S., et al. 1993. J. Biol. Chem. 268, 29.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-November-2013 JSW
SynonymsVMAT2 Inhibitor, Reserpine, Vesicular monoamine transporter (VMAT) Antagonist, Reserpine
DescriptionBinds the vesicular monoamine transporter (VMAT2) and acts as an irreversible transport inhibitor of biogenic amines. Used as a long-lasting bioamine depleter. Prevents bioamine transport into synaptic vesicles and chromaffin granules. Used as antihypertensive and antipsychotic drugs.
FormOff-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number50-55-5
Chemical formulaC₃₃H₄₀N₂O₉
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Harmful & Carcinogenic / Teratogenic
ReferencesOe, T., et al. 2010. Neurosci. 169, 1860.
Metzger, R. et al. 2002. Eur. J. Pharmacol. 456, 39.
Heslop, E., et al. 1999. Neuropharmacol. 38, 883.
Schuldiner, S., et al. 1993. J. Biol. Chem. 268, 29.