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504120 Reboxetine Mesylate - CAS 71620-89-8 - Calbiochem

Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
98769-84-7C₁₉H₂₃NO₃•CH₃SO₃H

Products

Catalog NumberPackaging Qty/Pack
5.04120.0001 Glass bottle 10 mg
Description
OverviewA potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and >10000 nM for rat NET, SERT and DAT, respectively). Displays >1000-fold selectivity over α-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant.
Catalogue Number504120
Brand Family Calbiochem®
Synonyms(2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholine methanesulfonate, Edronax, Vestra
References
ReferencesSacchetti, G., et al. 1999. Br. J. Pharmacol. 128, 1332.
Wong, E., et al. 2000. Biol. Psychiatry. 47, 818.
Millan, M., et al. 2001. J. Pharmacol. Exp. Ther. 298,565.
Owen, J., et al. 2003 Neurosci. Lett. 348, 171.
Product Information
CAS number98769-84-7
FormWhite solid
Hill FormulaC₁₉H₂₃NO₃•CH₃SO₃H
Chemical formulaC₁₉H₂₃NO₃•CH₃SO₃H
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetNoradrenalin transporter
Primary Target K<sub>i</sub>1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze 9-20°C. Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
5.04120.0001 04055977264289

Documentation

Reboxetine Mesylate - CAS 71620-89-8 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Reboxetine Mesylate - CAS 71620-89-8 - Calbiochem Certificates of Analysis

TitleLot Number
504120

References

Reference overview
Sacchetti, G., et al. 1999. Br. J. Pharmacol. 128, 1332.
Wong, E., et al. 2000. Biol. Psychiatry. 47, 818.
Millan, M., et al. 2001. J. Pharmacol. Exp. Ther. 298,565.
Owen, J., et al. 2003 Neurosci. Lett. 348, 171.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-August-2018 JSW
Synonyms(2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholine methanesulfonate, Edronax, Vestra
DescriptionA potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and >10000 nM for rat NET, SERT and DAT, respectively). Displays >1000-fold selectivity over α-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant.
FormWhite solid
CAS number98769-84-7
Chemical formulaC₁₉H₂₃NO₃•CH₃SO₃H
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityH₂O (20 mg/ml)
Storage Protect from light
Avoid freeze/thaw
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze 9-20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSacchetti, G., et al. 1999. Br. J. Pharmacol. 128, 1332.
Wong, E., et al. 2000. Biol. Psychiatry. 47, 818.
Millan, M., et al. 2001. J. Pharmacol. Exp. Ther. 298,565.
Owen, J., et al. 2003 Neurosci. Lett. 348, 171.