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554994 RHC-80267 - CAS 83654-05-1 - Calbiochem

554994
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Key Specifications Table

Empirical FormulaCAS #
C₂₀H₃₄N₄O₄ 83654-05-1

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554994-10MG
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      Plastic ampoule 10 mg
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      Description
      OverviewSelective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells. Also inhibits glucose- and carbachol-induced insulin release from intact islets. An inhibitor of Angiotensin II (Cat. No. 05-23-0101) and ATP-induced synthesis of 6-keto-prostaglandin F1α.
      Catalogue Number554994
      Brand Family Calbiochem®
      Synonyms1,6-bis(Cyclohexyloximinocarbonylamino)hexane
      References
      ReferencesShinoda, J., et al. 1997. Arterioscler. Thromb. Vasc. Biol. 17, 295.
      Shinoda, J., et al. 1997. Eur. J. Endocrinol. 136, 207.
      Konrad, R.J., et al. 1994. Biochemistry 33, 13284.
      Mason-Garcia, M., et al. 1992. Am. J. Physiol. 262, C1197.
      Balsinde, J., et al. 1991. J. Biol. Chem. 266, 15638.
      Product Information
      CAS number83654-05-1
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₂₀H₃₄N₄O₄
      Chemical formulaC₂₀H₃₄N₄O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetDAG lipase
      Primary Target IC<sub>50</sub>4 nM against DAG lipase activity in canine platelets
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      RHC-80267 - CAS 83654-05-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      RHC-80267 - CAS 83654-05-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      554994

      References

      Reference overview
      Shinoda, J., et al. 1997. Arterioscler. Thromb. Vasc. Biol. 17, 295.
      Shinoda, J., et al. 1997. Eur. J. Endocrinol. 136, 207.
      Konrad, R.J., et al. 1994. Biochemistry 33, 13284.
      Mason-Garcia, M., et al. 1992. Am. J. Physiol. 262, C1197.
      Balsinde, J., et al. 1991. J. Biol. Chem. 266, 15638.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-April-2011 RFH
      Synonyms1,6-bis(Cyclohexyloximinocarbonylamino)hexane
      DescriptionSelective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells. Also inhibits glucose- and carbachol-induced insulin release from intact islets. An inhibitor of Angiotensin II and ATP-induced synthesis of 6-keto-prostaglandin F1α.
      FormWhite to off-white solid
      CAS number83654-05-1
      Chemical formulaC₂₀H₃₄N₄O₄
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (25 mg/ml) or ethanol (25 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesShinoda, J., et al. 1997. Arterioscler. Thromb. Vasc. Biol. 17, 295.
      Shinoda, J., et al. 1997. Eur. J. Endocrinol. 136, 207.
      Konrad, R.J., et al. 1994. Biochemistry 33, 13284.
      Mason-Garcia, M., et al. 1992. Am. J. Physiol. 262, C1197.
      Balsinde, J., et al. 1991. J. Biol. Chem. 266, 15638.