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504839 (R)-CPP - CAS 126453-07-4 - Calbiochem

504839
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
126453-07-4C₈H₁₇N₂O₅P

Products

Catalog NumberPackaging Qty/Pack
5.04839.0001 Glass bottle 10 mg
Description
OverviewA highly potent antagonist slightly selective for NR2A over other subtype NMDA receptors (Ki = 0.041, 0.27, 0.63 and 1.99 µM for NMDA subtypes NR2A, NR2B, NR2C, and NR2D, respectively). Commonly used for various research in brain functions and disorders that neurotransmissions via NMDA receptors are involved.
Catalogue Number504839
Brand Family Calbiochem®
Synonyms(R)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid
References
ReferencesMurphy, R., et al. 2012. Psychopharmacol. 219, 401.
Paoletti, P., et al. 2007. Curr. Opin. Pharmacol. 7, 47.
Feng, B., et al. 2004. Br. J. Pharmacol. 141, 508.
Lowe, A., et al. 1990. Neurosci. Lett. 113, 315.
Product Information
CAS number126453-07-4
FormOff-white solid
Hill FormulaC₈H₁₇N₂O₅P
Chemical formulaC₈H₁₇N₂O₅P
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetNMDA receptors
Primary Target K<sub>i</sub>0.041, 0.27, 0.63 and 1.99 →M for NMDA subtypes NR2A, NR2B, NR2C, and NR2D, respectively.
Purity≥98% by NMR
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
5.04839.0001 04055977243567

Documentation

(R)-CPP - CAS 126453-07-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Murphy, R., et al. 2012. Psychopharmacol. 219, 401.
Paoletti, P., et al. 2007. Curr. Opin. Pharmacol. 7, 47.
Feng, B., et al. 2004. Br. J. Pharmacol. 141, 508.
Lowe, A., et al. 1990. Neurosci. Lett. 113, 315.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-July-2013 JSW
Synonyms(R)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid
DescriptionA highly potent antagonist slightly selective for NR2A over other subtype NMDA receptors (Ki = 0.041, 0.27, 0.63 and 1.99 µM for NMDA subtypes NR2A, NR2B, NR2C, and NR2D, respectively). Commonly used for various research in brain functions and disorders that neurotransmissions via NMDA receptors are involved.
FormOff-white solid
CAS number126453-07-4
Chemical formulaC₈H₁₇N₂O₅P
Structure formulaStructure formula
Purity≥98% by NMR
SolubilityH₂O (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesMurphy, R., et al. 2012. Psychopharmacol. 219, 401.
Paoletti, P., et al. 2007. Curr. Opin. Pharmacol. 7, 47.
Feng, B., et al. 2004. Br. J. Pharmacol. 141, 508.
Lowe, A., et al. 1990. Neurosci. Lett. 113, 315.