505873 (R)-Baclofen - CAS 69308-37-8 - Calbiochem

505873
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Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₁₀H₁₂ClNO₂ 69308-37-8

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      Glass bottle 10 mg
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      Description
      OverviewA selective agonist of GABAB receptors that is shown to activate K+ conductance in hippocampal neurons. Also acts as an antispastic agent and a skeletal muscle relaxant. It is also an experimental drug to treat autism.
      Catalogue Number505873
      Brand Family Calbiochem®
      SynonymsSTX 209, GABAB Agonist, Baclofen, Arbaclofen
      References
      ReferencesSodickson, D.L., et al., 1996. J. Neurosci. 16, 6374.
      Ahuja, S. et al., 1985. Analytical Profile of Drug Substances 14, 527.
      Product Information
      CAS number69308-37-8
      FormOff-white solid
      Hill FormulaC₁₀H₁₂ClNO₂
      Chemical formulaC₁₀H₁₂ClNO₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGABAB
      Purity≥98% by Chiral HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 25

      Toxic if swallowed.
      S PhraseS: 46

      If swallowed, seek medical advice immediately and show this container or label.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      (R)-Baclofen - CAS 69308-37-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Sodickson, D.L., et al., 1996. J. Neurosci. 16, 6374.
      Ahuja, S. et al., 1985. Analytical Profile of Drug Substances 14, 527.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-September-2013 JSW
      SynonymsSTX 209, GABAB Agonist, Baclofen, Arbaclofen
      DescriptionA selective agonist of GABAB receptors that is shown to activate K+ conductance in hippocampal neurons. Also acts as an antispastic agent and a skeletal muscle relaxant. It is also an experimental drug to treat autism.
      FormOff-white solid
      CAS number69308-37-8
      Chemical formulaC₁₀H₁₂ClNO₂
      Structure formulaStructure formula
      Purity≥98% by Chiral HPLC
      SolubilityH₂O
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Toxic
      ReferencesSodickson, D.L., et al., 1996. J. Neurosci. 16, 6374.
      Ahuja, S. et al., 1985. Analytical Profile of Drug Substances 14, 527.