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504631 Quisqualic acid - CAS 52809-07-1 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: β-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine

Primary Target: Group II and III mGlu receptors
504631
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
52809-07-1C₅H₇N₃O₅

Products

Catalog NumberPackaging Qty/Pack
5.04631.0001 Glass bottle 1 mg
Description
OverviewA potent agonist highly selective for group I (EC50 ≤3 µM) over group II and III mGlu receptors (EC50 >40 µM) and a potent agonist of AMPA receptors. Often used for inducing excitotoxic lesions of basal forebrain cholinergic neurons and spinal neurons.
Catalogue Number504631
Brand Family Calbiochem®
Synonymsβ-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
References
ReferencesJin, R., et al. 2012. Biochemistry. 41, 15635.
Kuang, D., et al. 2006. Biochem. & Biophys. Res. Comm. 345, 1.
Zhang, W., et al. 2006. Biophysical J. 91, 1336.
Muir, J., et al. 1993. Behav. Brain Res. 57, 123.
Product Information
CAS number52809-07-1
FormWhite powder
Hill FormulaC₅H₇N₃O₅
Chemical formulaC₅H₇N₃O₅
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target Group II and III mGlu receptors
Purity≥98% by TLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Quisqualic acid - CAS 52809-07-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Jin, R., et al. 2012. Biochemistry. 41, 15635.
Kuang, D., et al. 2006. Biochem. & Biophys. Res. Comm. 345, 1.
Zhang, W., et al. 2006. Biophysical J. 91, 1336.
Muir, J., et al. 1993. Behav. Brain Res. 57, 123.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-June-2013 JSW
Synonymsβ-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
DescriptionA potent agonist highly selective for group I (EC50 ≤3 µM) over group II and III mGlu receptors (EC50 >40 µM) and a potent agonist of AMPA receptors. Often used for inducing excitotoxic lesions of basal forebrain cholinergic neurons and spinal neurons.
FormWhite powder
CAS number52809-07-1
Chemical formulaC₅H₇N₃O₅
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityH₂O (0.5 mg/ml), 1M NH₄OH (20 mg/ml) or 0.1M HCl (1.4 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesJin, R., et al. 2012. Biochemistry. 41, 15635.
Kuang, D., et al. 2006. Biochem. & Biophys. Res. Comm. 345, 1.
Zhang, W., et al. 2006. Biophysical J. 91, 1336.
Muir, J., et al. 1993. Behav. Brain Res. 57, 123.