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104871 Potassium dihydrogen phosphate

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
7778-77-0 231-913-4 H₂KO₄P KH₂PO₄ 136.08 g/mol Ph Eur,BP,JPC,NF,E 340

Pricing & Availability

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1048710001
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      1048711000
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          1.04871.5000
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              1048719029
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                  1048719050
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                      1048719052
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                          Plastic drum 50 kg
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                          1048719100
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                              Drypour - Plastic drum 100 kg
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                              Description
                              Catalogue Number104871
                              Synonymsmono-Potassium orthophosphate, Potassium biphosphate, Potassium phosphate monobasic
                              References
                              Product Information
                              CAS number7778-77-0
                              EC number231-913-4
                              GradePh Eur,BP,JPC,NF,E 340
                              Hill FormulaH₂KO₄P
                              Chemical formulaKH₂PO₄
                              Molar Mass136.08 g/mol
                              HS Code2835 24 00
                              Quality LevelMQ500
                              Applications
                              Biological Information
                              Physicochemical Information
                              Density2.33 g/cm3 (21.5 °C)
                              Melting Point253 °C (decomposition)
                              pH value4.2 - 4.6 (20 g/l, H₂O, 20 °C)
                              Bulk density1200 kg/m3
                              Solubility208 g/l
                              Dimensions
                              Materials Information
                              Toxicological Information
                              LD 50 dermalLD50 Rabbit > 4640 mg/kg
                              Safety Information according to GHS
                              Precautionary Statement(s)P260: Do not breathe dust.
                              RTECSTC6615500
                              Storage class10 - 13 Other liquids and solids
                              WGKWGK 1 slightly hazardous to water
                              Disposal14
                              Inorganic salts: Container I. Neutral solutions of the these salts: Container D. Before placing in Container D, check the pH with pH-Universal indicator strips (Item No. 109535).
                              Safety Information
                              S PhraseS 22
                              Do not breathe dust.
                              Product Usage Statements
                              Storage and Shipping Information
                              StorageStore at +2°C to +30°C.
                              Packaging Information
                              Transport Information
                              Declaration (railroad and road) ADR, RIDKein Gefahrgut
                              Declaration (transport by air) IATA-DGRNo Dangerous Good
                              Declaration (transport by sea) IMDG-CodeNo Dangerous Good
                              Supplemental Information
                              Specifications
                              Assay (alkalimetric, calculated on dried substance)98.0 - 100.5 %
                              Assay (alkalimetric; dried substance)≥ 99.0 %
                              Appearance of solutionpasses test
                              Identitypasses test
                              Insoluble substances≤ 0.2 %
                              pH-value (1 %; water)4.2 - 4.8
                              pH-value (2 %; water)4.2 - 4.6
                              pH-value (5 %; water)4.2 - 4.5
                              Carbonatepasses test
                              Condensed phosphatepasses test
                              Chloride (Cl)≤ 0.009 %
                              Fluoride (F)≤ 0.0010 %
                              Sulfate (SO₄)≤ 0.017 %
                              Heavy metals (as Pb)≤ 0.0010 %
                              Al (Aluminium)≤ 0.0005 %
                              As (Arsenic)≤ 0.0001 %
                              Cd (Cadmium)≤ 0.0001 %
                              Fe (Iron)≤ 0.0010 %
                              Hg (Mercury)≤ 0.0001 %
                              Na (Sodium)
                              ≤ 0.1 %
                              passes test
                              Pb (Lead)≤ 0.0001 %
                              Residual solvents (ICH Q3C)excluded by manufacturing process
                              Reducing substancespasses test
                              Loss on drying (105 °C)≤ 0.5 %
                              Loss on drying (130 °C)≤ 1.0 %
                              Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
                              Corresponds to Ph Eur, BP, JPC, NF, E 340
                              Conforms to the purity criteria on food additives according to the current European Commission Regulation.

                              Documentation

                              Material Qualification Dossier

                              Title

                              Quality Management Dossier

                              Title

                              Operational Excellence Dossier

                              Title

                              Potassium dihydrogen phosphate SDS

                              Title

                              Safety Data Sheet (SDS) 

                              Potassium dihydrogen phosphate Certificates of Analysis

                              Product Number PackagingSpecificationLot Number
                              1048710001 Plastic bottlePDF Specification Document
                              1048711000 Plastic bottlePDF Specification Document
                              1.04871.5000 Plastic bottlePDF Specification Document
                              1048719029 Double PE SackPDF Specification Document
                              1048719050 Fibre cartonPDF Specification Document
                              1048719052 Plastic drumPDF Specification Document
                              1048719100 Drypour - Plastic drumPDF Specification Document

                              Certificates

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                              MultiPharmTM Minerals for Solid Dosage Forms

                              Technical Info

                              Title
                              1.04871 Change Notification Letter

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                              Small Molecule Pharmaceuticals > Formulation > Solid Dosage Form > pH Adjustment
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                              Small Molecule Pharmaceuticals > Formulation > Solid Dosage Form > Ingredients-solid
                              Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers