505316 PHA-543,613 - CAS 478149-53-0 - Calbiochem

505316
View Pricing & Availability

Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₁₅H₁₇N₃O₂ 478149-53-0

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
5.05316.0001
Retrieving availability...
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Glass bottle 5 mg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity needs to be mulitiple of
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      Description
      OverviewA potent agonist highly selective for α7 nicotinic acetylcholine receptor (α7 nAChR). Bioavaible admitted orally. Widely used in studies of the functional roles of α7 nAChR in learning and memory, sensory gating, and cognitive functions as well as Schizophrenia and Alzheimer′s disease.
      Catalogue Number505316
      Brand Family Calbiochem®
      SynonymsN-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, Alpha 7 Nicotinic Acetylcholine Receptor (α7 nAChR) Agonist, PHA-543613
      References
      ReferencesMazurov, A., et al., 2011. J. Med. Chem. 54, 7943.
      Wishka, G., et al., 2006. J. Med. Chem. 49, 4425.
      Faghih, R., et al., 2008. J. Med. Chem. 51, 701.
      Product Information
      CAS number478149-53-0
      FormWhite powder
      Hill FormulaC₁₅H₁₇N₃O₂
      Chemical formulaC₁₅H₁₇N₃O₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetα7 nAChR
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      PHA-543,613 - CAS 478149-53-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Mazurov, A., et al., 2011. J. Med. Chem. 54, 7943.
      Wishka, G., et al., 2006. J. Med. Chem. 49, 4425.
      Faghih, R., et al., 2008. J. Med. Chem. 51, 701.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-July-2013 JSW
      SynonymsN-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, Alpha 7 Nicotinic Acetylcholine Receptor (α7 nAChR) Agonist, PHA-543613
      DescriptionA potent agonist highly selective for α7 nicotinic acetylcholine receptor (α7 nAChR). Bioavaible admitted orally. Widely used in studies of the functional roles of α7 nAChR in learning and memory, sensory gating, and cognitive functions as well as Schizophrenia and Alzheimer′s disease.
      FormWhite powder
      CAS number478149-53-0
      Chemical formulaC₁₅H₁₇N₃O₂
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (20 mg/ml)
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesMazurov, A., et al., 2011. J. Med. Chem. 54, 7943.
      Wishka, G., et al., 2006. J. Med. Chem. 49, 4425.
      Faghih, R., et al., 2008. J. Med. Chem. 51, 701.