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496260 Oncostatin M, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhOSM

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496260
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Overview

Replacement Information

Products

Catalog NumberPackaging Qty/Pack
496260-10UG Plastic ampoule 10 μg
Description
OverviewRecombinant, human oncostatin M expressed in E. coli. Pleiotropic cytokine which inhibits growth of A375 melanoma cells and mouse M1 myeloid leukemic cells. Enhances the growth of both endothelial and hematopoietic cells. Has also been reported to have growth stimulatory activities on normal fibroblasts, AIDS-Kaposis sarcoma cells, and a human erythroleukemic cell line, TF-1.
Catalogue Number496260
Brand Family Calbiochem®
SynonymsrhOSM
References
ReferencesBoileau, C., et al. 2000. J. Immunol. 164, 5713.
Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.
Product Information
CAS number106956-32-5
FormLyophilized
FormulationLyophilized from sterile-filtered 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhOSM.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀ = 0.15-0.30 ng/ml as measured in a cell proliferation assay using a factor-dependent human erythroleukemic cell line, TF-1
Purity≥97% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: ≤1 EU/µg rhOSM
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Oncostatin M, Human, Recombinant, E. coli SDS

Title

Safety Data Sheet (SDS) 

Oncostatin M, Human, Recombinant, E. coli Certificates of Analysis

TitleLot Number
496260

References

Reference overview
Boileau, C., et al. 2000. J. Immunol. 164, 5713.
Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-August-2008 RFH
SynonymsrhOSM
DescriptionRecombinant, human oncostatin M expressed in E. coli. Pleiotropic cytokine which inhibits growth of A375 melanoma cells and mouse M1 myeloid leukemic cells. Has also been reported to have growth stimulatory activities on normal fibroblasts, AIDS-Kaposi's sarcoma cells, and human erythroleukemia cell line, TF-1.
FormLyophilized
FormulationLyophilized from sterile-filtered 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhOSM.
CAS number106956-32-5
Purity≥97% by SDS-PAGE
ContaminantsEndotoxin: ≤1 EU/µg rhOSM
Biological activityED₅₀ = 0.15-0.30 ng/ml as measured in a cell proliferation assay using a factor-dependent human erythroleukemic cell line, TF-1
SolubilityReconstitute to a final concentration of ≥10 µg/ml in sterile PBS containing ≥0.1% BSA or HSA.
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.
Toxicity Standard Handling
ReferencesBoileau, C., et al. 2000. J. Immunol. 164, 5713.
Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.