01-170 NGF 7S Protein, mouse

01-170
100 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Replacement Information

      Key Specifications Table

      Key ApplicationsSpeciesSource
      CULT Mouse Male mouse submaxillary glands
      Description
      Catalogue Number01-170
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionNGF 7S Protein, mouse
      References
      Product Information
      PresentationLyophilized.
      Quality LevelMQ100
      Applications
      ApplicationThe mouse NGF 7S Protein( or nerve growth factor 7S) is available in a 100 µg format.
      Key Applications
      • Cell Culture
      Biological Information
      SourceMale mouse submaxillary glands
      Entrez Gene Number
      Entrez Gene SummaryThis gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
      Gene Symbol
      • NGFB
      • HSAN5
      • NGF
      • Beta-NGF
      • MGC161426
      • MGC161428
      Purification MethodSterilized through a 0.2 micron membrane filter
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01138 # Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons.
      SIZE: 241 amino acids; 26959 Da
      SUBUNIT: Homodimer.
      SUBCELLULAR LOCATION: Secreted.
      DISEASE: SwissProt: P01138 # Defects in NGFB are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. Hereditary sensory and autonomic neuropathies are characterized by loss of pain sensation in combination with other sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self- mutilation. The autonomic involvement is variable.
      SIMILARITY: SwissProt: P01138 ## Belongs to the NGF-beta family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      NGF 7S Protein, mouse SDS

      Title

      Safety Data Sheet (SDS) 

      NGF 7S Protein, mouse Certificates of Analysis

      TitleLot Number
      NGF 7S, mouse2941112
      NGF 7S, mouse3043063
      NGF 7S, mouse - 24264702426470
      NGF 7S, mouse - 1514415144
      NGF 7S, mouse - 1826618266
      NGF 7S, mouse - 1994419944
      NGF 7S, mouse - 21596352159635
      NGF 7S, mouse - 22726752272675
      NGF 7S, mouse - 2321723217
      NGF 7S, mouse - 2405624056

      References

      Reference overviewApplicationPub Med ID
      Localization of the angiopoietin receptors Tie-1 and Tie-2 on the primary cilia in the female reproductive organs.
      Stefan C Teilmann,Søren T Christensen
      Cell biology international  29  2005

      Show Abstract
      15893943 15893943
      Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: time course and modification by (-)-deprenyl
      Wadia, J. S., et al
      J Neurosci, 18:932-47 (1998)  1998

      Cell Culture9437015 9437015
      Selective regulation of agrin mRNA induction and alternative splicing in PC12 cells by Ras-dependent actions of nerve growth factor
      Smith, M. A., et al
      J Biol Chem, 272:15675-81 (1997)  1997

      Cell Culture9188458 9188458
      The nerve growth factor thirty-five years later.
      Levi-Montalcini, R
      In Vitro Cell. Dev. Biol., 23: 227-38 (1987)  1987

      3553145 3553145
      Nerve growth factor acts in brain.
      Marx, J L
      Science, 232: 1341-2 (1986)  1986

      2940683 2940683
      The biological activity of cross-linked beta nerve growth factor protein.
      Stach, R W and Shooter, E M
      J. Biol. Chem., 249: 6668-74 (1974)  1974

      4418144 4418144