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FCMAB178P Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c

FCMAB178P
100 tests  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMPhycoerythrinMonoclonal Antibody
      Description
      Catalogue NumberFCMAB178P
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c
      Alternate Names
      • Integrin alpha-M
      • Cell surface glycoprotein MAC-1 subunit alpha
      • CR-3 alpha chain
      • Leukocyte adhesion receptor MO1
      • Neutrophil adherence receptor
      • CD11 antigen-like family member B
      Background InformationCD11b is the 165 kDa α-chain of the Mac-1 complex. The molecule, also called CR3, functions as a cell surface receptor for the C3bi complement fragment. There is evidence that CD11b can bind fibrinogen in addition to C3bi (Wright,1988). Two binding sites have now been reported, one recognizing lipopolysaccharide, and the other protein ligands containing the arg-gly-asp sequence (Wright, 1989). Binding of the coagulation factor X has also been suggested as an additional receptor role of CD11b (Altieri,1988). This protein belings to a family of related heterodimeric proteins designated CD11 in the classification system for human leucocyte differentiation antigens, which shares a common β-chain with a MW of 95 kDa (CD18). Besides the C3bi receptor, this protein family contains two other members, leucocyte function associated-1 (LFA-1, C11a) antigen and p150,95 protein (CD11c) (Sanchez-Madrid,1983).
      References
      Product Information
      FormatPhycoerythrin
      Control
      • PBMCs
      PresentationPurified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
      Quality LevelMQ100
      Applications
      ApplicationMilli-Mark Anti-CD11B-PE Antibody, clone 2LPM19c detects level of CD11B & has been published & validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenPurified iC3b receptor.
      Clone2LPM19c
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD11b antigen.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight165 kDa (Wright, 1988)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using human PBMCs
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c SDS

      Title

      Safety Data Sheet (SDS) 

      Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-CD11B-PE, clone 2LPM19c - 1947165 1947165
      Milli-Mark Anti-CD11B-PE, clone 2LPM19c - 1994398 1994398
      Milli-Mark Anti-CD11B-PE, clone 2LPM19c - 2009437 2009437
      Milli-Mark Anti-CD11B-PE, clone 2LPM19c - NRG1781532 NRG1781532
      Milli-Mark Anti-CD11B-PE, clone 2LPM19c - NRG1781533 NRG1781533
      Milli-Mark™ Anti-CD11B-PE, -2529365 2529365
      Milli-Mark™ Anti-CD11B-PE, -2570685 2570685
      Milli-Mark™ Anti-CD11B-PE, -2578623 2578623
      Milli-Mark™ Anti-CD11B-PE, -2645970 2645970
      Milli-Mark™ Anti-CD11B-PE, clone 2LPM19c - 3383970 3383970

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies