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509705 L-Serine-O-phosphate - CAS 407-41-0 - Calbiochem

A potent agonist for group III mGlu receptor subtype 4, 6, and 8.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: L-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate

Primary Target: mGlu₄, mGlu₆, mGlu₈
509705
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
407-41-0C₃H₈NO₆P

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      Description
      OverviewA potent agonist for group III mGlu receptor subtype 4, 6, and 8 (EC50 = 1-4, 3, and 2 µM for mGlu4, mGlu6, mGlu8, respectively); but not for subtype 7 (EC50 = 160-1200 µM). Inhibits proliferation and enhances neuronal differentiation in progenitor cells. Widely used to study presynaptic inhibitory modulation of the excitatory glutamatergic transmission at retina and central nervous systems.

      Please note that the molecular weight for this compound is batch-specific due to variable water content.
      Catalogue Number509705
      Brand Family Calbiochem®
      SynonymsL-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate
      References
      ReferencesEriksen, L., et al. 1995. Br. J. Pharmacol. 116, 3279.
      Thoreson, W., et al. 1995. Brain Res. 676, 93.
      Bruno, V., et al. 1996. Eur. J. Pharmacol. 310, 61.
      Saxe, J., et al. 2007. Chem. Biol. 14, 1019.
      Nakajima, Y., 1993. J. Biol. Chem. 268, 11868.
      Product Information
      CAS number407-41-0
      FormOff-white powder
      Hill FormulaC₃H₈NO₆P
      Chemical formulaC₃H₈NO₆P
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetmGlu₄, mGlu₆, mGlu₈
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      L-Serine-O-phosphate - CAS 407-41-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Eriksen, L., et al. 1995. Br. J. Pharmacol. 116, 3279.
      Thoreson, W., et al. 1995. Brain Res. 676, 93.
      Bruno, V., et al. 1996. Eur. J. Pharmacol. 310, 61.
      Saxe, J., et al. 2007. Chem. Biol. 14, 1019.
      Nakajima, Y., 1993. J. Biol. Chem. 268, 11868.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-April-2014 JSW
      SynonymsL-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate
      DescriptionA potent agonist for group III mGlu receptor subtype 4, 6, and 8 (EC50 = 1-4, 3, and 2 µM for mGlu4, mGlu6, mGlu8, respectively); but not for subtype 7 (EC50 = 160-1200 µM). Inhibits proliferation and enhances neuronal differentiation in progenitor cells. Widely used to study presynaptic inhibitory modulation of the excitatory glutamatergic transmission at retina and central nervous systems.
      FormOff-white powder
      Intert gas (Yes/No) Packaged under inert gas
      CAS number407-41-0
      Chemical formulaC₃H₈NO₆P
      Purity≥98% by HPLC
      SolubilityH₂O (50 mg/ml)
      Storage +15°C to +30°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesEriksen, L., et al. 1995. Br. J. Pharmacol. 116, 3279.
      Thoreson, W., et al. 1995. Brain Res. 676, 93.
      Bruno, V., et al. 1996. Eur. J. Pharmacol. 310, 61.
      Saxe, J., et al. 2007. Chem. Biol. 14, 1019.
      Nakajima, Y., 1993. J. Biol. Chem. 268, 11868.