509705 L-Serine-O-phosphate - CAS 407-41-0 - Calbiochem

A potent agonist for group III mGlu receptor subtype 4, 6, and 8.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: L-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate

Primary Target: mGlu₄, mGlu₆, mGlu₈
509705
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₃H₈NO₆P 407-41-0

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      5.09705.0001
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          		 Glass bottle 1 gm
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          Description
          OverviewA potent agonist for group III mGlu receptor subtype 4, 6, and 8 (EC50 = 1-4, 3, and 2 µM for mGlu4, mGlu6, mGlu8, respectively); but not for subtype 7 (EC50 = 160-1200 µM). Inhibits proliferation and enhances neuronal differentiation in progenitor cells. Widely used to study presynaptic inhibitory modulation of the excitatory glutamatergic transmission at retina and central nervous systems.

          Please note that the molecular weight for this compound is batch-specific due to variable water content.
          Catalogue Number509705
          Brand Family Calbiochem®
          SynonymsL-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate
          References
          ReferencesEriksen, L., et al. 1995. Br. J. Pharmacol. 116, 3279.
          Thoreson, W., et al. 1995. Brain Res. 676, 93.
          Bruno, V., et al. 1996. Eur. J. Pharmacol. 310, 61.
          Saxe, J., et al. 2007. Chem. Biol. 14, 1019.
          Nakajima, Y., 1993. J. Biol. Chem. 268, 11868.
          Product Information
          CAS number407-41-0
          FormOff-white powder
          Hill FormulaC₃H₈NO₆P
          Chemical formulaC₃H₈NO₆P
          Applications
          Biological Information
          Primary TargetmGlu₄, mGlu₆, mGlu₈
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          L-Serine-O-phosphate - CAS 407-41-0 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Eriksen, L., et al. 1995. Br. J. Pharmacol. 116, 3279.
          Thoreson, W., et al. 1995. Brain Res. 676, 93.
          Bruno, V., et al. 1996. Eur. J. Pharmacol. 310, 61.
          Saxe, J., et al. 2007. Chem. Biol. 14, 1019.
          Nakajima, Y., 1993. J. Biol. Chem. 268, 11868.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-April-2014 JSW
          SynonymsL-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate
          DescriptionA potent agonist for group III mGlu receptor subtype 4, 6, and 8 (EC50 = 1-4, 3, and 2 µM for mGlu4, mGlu6, mGlu8, respectively); but not for subtype 7 (EC50 = 160-1200 µM). Inhibits proliferation and enhances neuronal differentiation in progenitor cells. Widely used to study presynaptic inhibitory modulation of the excitatory glutamatergic transmission at retina and central nervous systems.
          FormOff-white powder
          Intert gas (Yes/No) Packaged under inert gas
          CAS number407-41-0
          Chemical formulaC₃H₈NO₆P
          Purity≥98% by HPLC
          SolubilityH₂O (50 mg/ml)
          Storage +15°C to +30°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesEriksen, L., et al. 1995. Br. J. Pharmacol. 116, 3279.
          Thoreson, W., et al. 1995. Brain Res. 676, 93.
          Bruno, V., et al. 1996. Eur. J. Pharmacol. 310, 61.
          Saxe, J., et al. 2007. Chem. Biol. 14, 1019.
          Nakajima, Y., 1993. J. Biol. Chem. 268, 11868.