420311 Kanamycin Sulfate, Streptomyces kanamyceticus - CAS 25389-94-0 - Calbiochem

420311
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Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₁₈H₃₆N₄O₁₁ · H₂SO₄ 25389-94-0

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420311-25GM
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      420311-5GM
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          Description
          OverviewContains more than 98% kanamycin A. An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 30S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.
          Potency: ≥750 µg/mg
          Catalogue Number420311
          Brand Family Calbiochem®
          SynonymsKamycin
          References
          ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
          Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
          Cardon, G.H., et al. 1993. Plant J. 3, 773.
          Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
          Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
          Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
          Umezawa, S., et al. 1968. J. Antibiot. 21, 367.
          Product Information
          CAS number25389-94-0
          FormWhite to off-white solid
          Hill FormulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
          Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary Targetprotein biosynthesis
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSNZ3225030
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Kanamycin Sulfate, Streptomyces kanamyceticus - CAS 25389-94-0 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Kanamycin Sulfate, Streptomyces kanamyceticus - CAS 25389-94-0 - Calbiochem Certificates of Analysis

          TitleLot Number
          420311

          References

          Reference overview
          Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
          Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
          Cardon, G.H., et al. 1993. Plant J. 3, 773.
          Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
          Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
          Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
          Umezawa, S., et al. 1968. J. Antibiot. 21, 367.

          Brochure

          Title
          Antibiotics Profiler
          Bulk packaging
          Overnight Express Autoinduction Systems

          Citations

          Title
        • Thomas S. Lendvay, et al. (2007) Compensatory paracrine mechanisms that define the urothelial response to injury in partial bladder outlet obstruction. American Journal of Physiology: Renal 293, F1147-F1156.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision24-September-2010 JSW
          SynonymsKamycin
          DescriptionContains more than 98% kanamycin A. An aminoglycoside antibiotic affective against gram-positive and gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 70S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.
          FormWhite to off-white solid
          CAS number25389-94-0
          RTECSNZ3225030
          Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
          Structure formulaStructure formula
          SolubilityH₂O (10 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Merck USA index14, 5281
          ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
          Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
          Cardon, G.H., et al. 1993. Plant J. 3, 773.
          Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
          Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
          Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
          Umezawa, S., et al. 1968. J. Antibiot. 21, 367.
          Citation
        • Thomas S. Lendvay, et al. (2007) Compensatory paracrine mechanisms that define the urothelial response to injury in partial bladder outlet obstruction. American Journal of Physiology: Renal 293, F1147-F1156.
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          Categories

          Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Protein Synthesis Inhibitors
          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Antibiotics > Antimicrobial Agents
          Life Science Research > Cell Culture and Systems > Antibiotics & Selection Agents