506169 InhibitorSelect™ p53 Pathway Regulators Panel

506169
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506169-1EA
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      Description
      OverviewA panel containing 18 potent, selective and cell-permeable inhibitors and 1 activator that is useful for the study of p53 pathway: 2 mg of ATM Kinase Inhibitor (Cat. No. 118500), 5 mg ATM/ATR Kinase Inhibitor (Cat. No. 118501), 10 mg of Anacardic Acid (Cat. No. 172050), 5 mg of Cdk1 Inhibitor IV, RO-3306 (Cat. No. 217699), 5 mg of Casein Kinase II Inhibitor III, TBCA (Cat. No. 218710), 1 mg of Chk2 Inhibitor II (Cat. No. 220486), 5 mg of Hdm2 E3 Ligase Inhibitor (Cat. No. 373225), 5 mg of JNK Inhibitor II (Cat. No. 420119), 1 mg of MDM2 Antagonist, Nutlin-3, Racemic (Cat. No. 444143), 10 mg of MDMX Inhibitor, SJ-172550 (Cat. No. 444155), 5 mg of MG-132 (Cat. No. 474790), 5 mg of p21-Activated Kinase Inhibitor III, IPA-3 (Cat. No. 506106), 5 mg of Pifithrin-α (Cat. No. 506132), 1 mg of PI-103 (Cat. No. 528100), 1 mg of PARP Inhibitor VIII, PJ34 (Cat. No. 528150), 10 mg of PPM1D Phosphatase Inhibitor (Cat. No. 529578), 10 mg of PRIMA-1 (Cat. No. 530050), 1 mg of Caspase Inhibitor I (Cat. No. 627610), and 1 mg Trichostatin A, Streptomyces sp. (Cat. No. 647925). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817). Supplied with a data sheet.
      Catalogue Number506169
      Brand Family Calbiochem®
      Application Data
      References
      ReferencesFeng, Z. and Levine, A.J., 2010. Trends Cell Biol. 20, 427.
      Wiman, K.G., 2010. Oncogene 29, 4245.
      Brown, C.J., et al. 2009. Nat. Rev. Cancer 9, 862.
      Dey, A., et al. 2008. Br. J. Cancer 98, 4.
      Levine, A.J., et al. 2006. Cell Death Differ. 13, 1027.
      Product Information
      FormSolid
      Hygroscopic Hygroscopic
      Quality LevelMQ100
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 22-36/37/38

      Harmful if swallowed.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Regulatory Review
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Each solutions is stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InhibitorSelect™ p53 Pathway Regulators Panel SDS

      Title

      Safety Data Sheet (SDS) 

      InhibitorSelect™ p53 Pathway Regulators Panel Certificates of Analysis

      TitleLot Number
      506169

      References

      Reference overview
      Feng, Z. and Levine, A.J., 2010. Trends Cell Biol. 20, 427.
      Wiman, K.G., 2010. Oncogene 29, 4245.
      Brown, C.J., et al. 2009. Nat. Rev. Cancer 9, 862.
      Dey, A., et al. 2008. Br. J. Cancer 98, 4.
      Levine, A.J., et al. 2006. Cell Death Differ. 13, 1027.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision29-Sepmtember-2011 RFH
      Application Data
      DescriptionA panel containing 18 potent, selective and cell-permeable inhibitors and 1 activator that is useful for the study of p53 pathway. The panel contains the following inhibitors/activator and 15 ml anhydrous DMSO for reconstitution:
      FormSolid
      Intert gas (Yes/No) Packaged under inert gas
      SolubilityDMSO (supplied). Please refer to information provided on the CD for reconstitution of individual inhibitors.
      Storage -20°C
      Hygroscopic
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Each solutions is stable for up to 3 months at -20°C.
      Toxicity Regulatory Review
      ReferencesFeng, Z. and Levine, A.J., 2010. Trends Cell Biol. 20, 427.
      Wiman, K.G., 2010. Oncogene 29, 4245.
      Brown, C.J., et al. 2009. Nat. Rev. Cancer 9, 862.
      Dey, A., et al. 2008. Br. J. Cancer 98, 4.
      Levine, A.J., et al. 2006. Cell Death Differ. 13, 1027.