401478 IκB Kinase Inactive Control Peptide, Cell-Permeable - Calbiochem

401478
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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₁₃₈H₂₂₉N₃₇O₄₃S

Pricing & Availability

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401478-1MG
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      Plastic ampoule 1 mg
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      Description
      OverviewAn inactive control for IκB Kinase Inhibitor Peptide (Cat. No. 401477). A 14-amino acid peptide corresponding to the mutated recognition sequence of IκB (Ser32→Ala and Ser36→Ala) fused to the hydrophobic region of the fibroblast growth factor signal peptide to aid in cellular delivery. Does not have any inhibitory effect on LPS-induced IκB degradation by IκB kinases (IKK) in RAW 264.7 cells at 50 µg/ml.
      Catalogue Number401478
      Brand Family Calbiochem®
      SynonymsAc-AAVALLPAVLLALLAPDDRHDAGLDAMKDE-NH₂
      References
      ReferencesSwaroop, N., et al. 2001. Pharm. Res. 18, 1631.
      Traenckner, E.B., et al. 1995. EMBO J. 14, 2876.
      Product Information
      ATP CompetitiveN
      FormOff-white to white solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₃₈H₂₂₉N₃₇O₄₃S
      Chemical formulaC₁₃₈H₂₂₉N₃₇O₄₃S
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAn inactive control for IκB Kinase Inhibitor Peptide
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Asp-Arg-His-Asp-Ala-Gly-Leu-Asp-Ala-Met-Lys-Asp-Glu-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      IκB Kinase Inactive Control Peptide, Cell-Permeable - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      IκB Kinase Inactive Control Peptide, Cell-Permeable - Calbiochem Certificates of Analysis

      TitleLot Number
      401478

      References

      Reference overview
      Swaroop, N., et al. 2001. Pharm. Res. 18, 1631.
      Traenckner, E.B., et al. 1995. EMBO J. 14, 2876.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-July-2014 JSW
      SynonymsAc-AAVALLPAVLLALLAPDDRHDAGLDAMKDE-NH₂
      DescriptionAn inactive control for IkB Kinase Inhibitor Peptide (Cat. No. 401477). A 14-amino acid peptide corresponding to the mutated recognition sequence of IkB (Ser32 → Ala and Ser36 → Ala), linked to the hydrophobic region of the fibroblast growth factor signal peptide to aid in cellular delivery. Does not have any inhibitory effect on LPS-induced IκB degradation by IκB kinases (IKK) in RAW 264.7 cells at 50 µg/ml.
      FormOff-white to white solid
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₃₈H₂₂₉N₃₇O₄₃S
      Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Asp-Arg-His-Asp-Ala-Gly-Leu-Asp-Ala-Met-Lys-Asp-Glu-NH₂
      Purity≥97% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSwaroop, N., et al. 2001. Pharm. Res. 18, 1631.
      Traenckner, E.B., et al. 1995. EMBO J. 14, 2876.