GF051 Granulocyte Colony-Stimulating Factor Protein, Recombinant human

GF051
10 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Key ApplicationsSpeciesSourcePurity
      CULT Human E.coli Greater than 98% by SDS-PAGE
      Description
      Catalogue NumberGF051
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionGranulocyte Colony-Stimulating Factor Protein, Recombinant human
      OverviewGranulocyte Colony-Stimulating Factor (G-CSF) is a potent stimulatory of bone marrow cells, especially those of neutrophil lineage. In addition, G-CSF can enhance the survival and activate the immunological functions of mature neutrophils. Human G-CSF is an 18.7 kDa protein containing 174 amino acid residues.
      Alternate Names
      • G-CSF
      References
      Product Information
      PresentationLyophilized from 5 mM Sodium Citrate, pH4.0.
      Quality LevelMQ100
      Applications
      ApplicationThe Granulocyte Colony-Stimulating Factor protein (or G-CSF Protein), Recombinant human, is a potent stimulatory of bone marrow cells, especially those of neutrophil lineage.
      Key Applications
      • Cell Culture
      Biological Information
      PurityGreater than 98% by SDS-PAGE
      SourceE.coli
      Specific ActivityGF051 is fully biologically active when compared to standards. The ED(50) was determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is <=0.1 ng/ml, corresponding to a specific activity of >=1x107 units/mg.
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for this gene.
      Gene Symbol
      • CSF3
      • Lenograstim
      • filgrastim
      • Filgrastim
      • lenograstim
      • MGC45931
      • Pluripoietin
      • G-CSF
      • pluripoietin
      • GCSF
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P09919 # Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
      SIZE: 207 amino acids; 22293 Da
      SUBUNIT: Monomer.
      SUBCELLULAR LOCATION: Secreted.
      PTM: O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).
      SIMILARITY: SwissProt: P09919 ## Belongs to the IL-6 superfamily.
      Stem Cell Type
      • Hematopoietic Stem Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute with sterile water to a concentration of 0.1-0.5 mg/mL. This solution can be diluted into other buffered solutions. Reconstituted GF051 should be stored in working aliquots at -20°C for up to 6 months. Further dilutions should be made into buffer containing carrier protein or medium containing serum.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Granulocyte Colony-Stimulating Factor Protein, Recombinant human SDS

      Title

      Safety Data Sheet (SDS) 

      Granulocyte Colony-Stimulating Factor Protein, Recombinant human Certificates of Analysis

      TitleLot Number
      IL031 -26337582633758
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR3170217
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR2953866
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR2891473
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR3041118
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR3093521
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR2922482
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR - 20180532018053
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR - 21960012196001
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR - LV1567630LV1567630

      Data Sheet

      Title
      RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR

      Related Products & Applications

      Product Families

      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors