344216 Sigma-AldrichFormyl Peptide Receptor-Like 1 Agonist, WKYMVm - Calbiochem
The Formyl Peptide Receptor-Like 1 Agonist, WKYMVm controls the biological activity of Formyl Peptide Receptor-Like 1. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
More>> The Formyl Peptide Receptor-Like 1 Agonist, WKYMVm controls the biological activity of Formyl Peptide Receptor-Like 1. This small molecule/inhibitor is primarily used for Activators/Inducers applications. Less<<Synonyms: H₂N-WKYMV-D-M-CONH₂, FPRL1 Agonist, WKYMVm
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Overview
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Products
Catalog Number | Packaging | Qty/Pack | |
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344216-5MG | Plastic ampoule | 5 mg |
Description | |
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Overview | A potent chemoattractant that enhances leukocyte activity via activation of Formyl Peptide Receptor-Like 1 (FPRL1). Shown to activate phospholipase C-mediated inositol phosphate formation in human U266 myeloma cells (EC50 = 510 pM). Also shown to stimulate inositol phosphate formation in U937 and HL60 cells, but has no effect on a variety of other cell lines (e.g. NIH3T3, PC12, Daudi, Sp2, Jurkat, H9, Molt-4, SupT-1, K562, and RBL-2H3). Stimulates phagocyte chemotaxis and [Ca2+] flux, and is more effective than fMLP (Cat. No. 05-22-2500) in generating superoxide in human neutrophils. Radioiodinatable at the tyrosine residue. |
Catalogue Number | 344216 |
Brand Family | Calbiochem® |
Synonyms | H₂N-WKYMV-D-M-CONH₂, FPRL1 Agonist, WKYMVm |
Product Information | |
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ATP Competitive | N |
Form | Lyophilized |
Formulation | Supplied as a trifluoroacetate salt. |
Hill Formula | C₄₁H₆₁N₉O₇S₂ |
Chemical formula | C₄₁H₆₁N₉O₇S₂ |
Hygroscopic | Hygroscopic |
Reversible | N |
Quality Level | MQ100 |
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Physicochemical Information | |
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Cell permeable | N |
Peptide Sequence | H-Trp-Lys-Tyr-Met-Val-D-Met-CONH₂ |
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Packaged under inert gas | Packaged under inert gas |
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Specifications |
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Global Trade Item Number | |
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Catalog Number | GTIN |
344216-5MG | 04055977215328 |
Documentation
Formyl Peptide Receptor-Like 1 Agonist, WKYMVm - Calbiochem SDS
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Formyl Peptide Receptor-Like 1 Agonist, WKYMVm - Calbiochem Certificates of Analysis
Title | Lot Number |
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344216 |
References
Reference overview |
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Bae, Y.S., et al. 2004. J. Immunol. 173, 607. Bae, Y.S., et al. 2003. Mol. Pharmacol. 64, 841. Le, Y., et al. 1999. J. Immunol. 163, 6777. Seo, J.K., et al. 1997. J. Immunol. 158, 1895. Baek, S.H., et al. 1996. J. Biol. Chem. 271, 8170. |