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341274 Factor H, Human

341274
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341274-250UG
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      Plastic ampoule 250 μg
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      Description
      OverviewNative factor H from human serum. Single-chain multi-functional glycoprotein present in normal human serum at about 500 µg/ml. Regulates formation and function of complement C3 and C5 convertase enzymes. A C3b-binding protein that does not exhibit enzymatic activity. Regulatory activity is attributed to its ability to recognize and bind to C3b fragments.
      Catalogue Number341274
      Brand Family Calbiochem®
      Synonymsβ1H Globulin
      References
      ReferencesZipfel, P.F., et al. 1999. Immunopharmacology 42, 53.
      Pangburn, M.K. and Muller-Eberhard, H.J. 1984. Springer Semin. Immunopathol. 7, 163.
      Fearon, D.T. and Austen, K.F. 1977. Proc. Natl. Acad. Sci. USA 74, 1683.
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.2.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      ContaminantsIgG, IgA, IgM, Factor I, Factor B, Factor P, C3, C4, or albumin (by Ouchterlony): ≤trace amounts
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Factor H, Human SDS

      Title

      Safety Data Sheet (SDS) 

      Factor H, Human Certificates of Analysis

      TitleLot Number
      341274

      References

      Reference overview
      Zipfel, P.F., et al. 1999. Immunopharmacology 42, 53.
      Pangburn, M.K. and Muller-Eberhard, H.J. 1984. Springer Semin. Immunopathol. 7, 163.
      Fearon, D.T. and Austen, K.F. 1977. Proc. Natl. Acad. Sci. USA 74, 1683.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision24-June-2008 RFH
      Synonymsβ1H Globulin
      DescriptionNative factor H from human serum. Single-chain glycoprotein present in normal human serum at about 500 µg/ml. Regulates formation and function of complement C3 and C5 convertase enzymes. A C3b-binding protein, not an enzyme. Regulatory activity is attributed to its ability to recognize and bind to C3b fragments.
      FormLiquid
      FormulationIn PBS, pH 7.2.
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥95% by SDS-PAGE
      ContaminantsIgG, IgA, IgM, Factor I, Factor B, Factor P, C3, C4, or albumin (by Ouchterlony): ≤trace amounts
      Storage ≤ -70°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesZipfel, P.F., et al. 1999. Immunopharmacology 42, 53.
      Pangburn, M.K. and Muller-Eberhard, H.J. 1984. Springer Semin. Immunopathol. 7, 163.
      Fearon, D.T. and Austen, K.F. 1977. Proc. Natl. Acad. Sci. USA 74, 1683.