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505483 FFN511 - CAS 1004548-96-2 - Calbiochem

505483
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Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₁₇H₂₀N₂O₂ 1004548-96-2

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      Description
      OverviewA fluorescent false neurotransmitter that acts as an optical tracer that inhibits serotonin binding to VMAT2-containing membranes (IC50 = 1 µM). Compound has been used to assess the functional status of TH positive neurons by fluorescent measurement of uptatke and release.
      Catalogue Number505483
      Brand Family Calbiochem®
      SynonymsFluorescent False Neurotransmitter 511, Vesicle Monoamine Transporter (VMAT2) Substrate, FFN511
      References
      ReferencesDulcis, D. et al. 2013. Science 340, 449.
      Gubernator, N. G. et al. 2009. Science 324, 1441.
      Product Information
      CAS number1004548-96-2
      FormYellow solid
      Hill FormulaC₁₇H₂₀N₂O₂
      Chemical formulaC₁₇H₂₀N₂O₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetVMAT2
      Primary Target IC<sub>50</sub>1 µ
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      FFN511 - CAS 1004548-96-2 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Dulcis, D. et al. 2013. Science 340, 449.
      Gubernator, N. G. et al. 2009. Science 324, 1441.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2013 JSW
      SynonymsFluorescent False Neurotransmitter 511, Vesicle Monoamine Transporter (VMAT2) Substrate, FFN511
      DescriptionA fluorescent false neurotransmitter that acts as an optical tracer that inhibits serotonin binding to VMAT2-containing membranes (IC50 = 1 µM). Compound has been used to assess the functional status of TH positive neurons by fluorescent measurement of uptatke and release.
      FormYellow solid
      CAS number1004548-96-2
      Chemical formulaC₁₇H₂₀N₂O₂
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (5 mM)
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesDulcis, D. et al. 2013. Science 340, 449.
      Gubernator, N. G. et al. 2009. Science 324, 1441.