01-407 Epidermal growth factor (EGF)

01-407
500 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Key ApplicationsSpeciesSource
      CULT Human Recombinant human DNA expressed in yeast
      Description
      Catalogue Number01-407
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionEpidermal growth factor (EGF)
      References
      Product Information
      PresentationLypholized from 100mM acetic acid with 3.5mg mannitol
      Quality LevelMQ100
      Applications
      ApplicationThis Epidermal growth factor (EGF) product is available in a 500 µg format.
      Key Applications
      • Cell Culture
      Biological Information
      SourceRecombinant human DNA expressed in yeast
      Entrez Gene Number
      Entrez Gene SummaryEpidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide.
      Gene Symbol
      • EGF
      • URG
      • urogastrone
      Purification MethodSterilized through a 0.2 micron membrane filter
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01133 # EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.
      SIZE: 1207 amino acids; 133946 Da
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      SIMILARITY: SwissProt: P01133 ## Contains 9 EGF-like domains. & Contains 9 LDL-receptor class B repeats.
      Stem Cell Type
      • Neural Stem Cells
      • Epithelial Cells
      • Mesenchymal Stem Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated in a 5-day growth assay using human foreskin fibroblasts
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size500 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Epidermal growth factor (EGF) Certificates of Analysis

      TitleLot Number
      EGF (Epidermal Growth Factor)2507184
      EGF (Epidermal Growth Factor) (human recombinant) - 2089009A2089009A
      EGF (Epidermal Growth Factor) (human recombinant) - 21133432113343
      EGF (Epidermal Growth Factor) (human recombinant) - 23908862390886
      EGF (Epidermal Growth Factor) (human recombinant) - 23909112390911
      EGF (Epidermal Growth Factor) (human recombinant) - 24441322444132
      EGF (Epidermal Growth Factor) (human recombinant)3109204
      EGF (Epidermal Growth Factor) (human recombinant)3126972
      EGF (Epidermal Growth Factor) (human recombinant)3156020
      EGF (Epidermal Growth Factor) (human recombinant)2923260

      References

      Reference overviewApplicationPub Med ID
      Kinase suppressor of Ras signals through Thr269 of c-Raf-1.
      Xing, H R and Kolesnick, R
      J. Biol. Chem., 276: 9733-41 (2001)  2001

      Show Abstract
      Cell Culture11134016 11134016

      Related Products & Applications

      Product Families

      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors