212385 Sigma-AldrichCarbachol - CAS 51-83-2 - Calbiochem

An unsubstituted carbamoyl ester that acts as an agonist for nicotinic and muscarinic acetylcholine receptors.

Carbachol - CAS 51-83-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA
References
Data Sheet

Synonyms: Carbamoylcholine Chloride

Primary Target: Agonist for nicotinic and muscarinic acetylcholine receptors

Recommended Products

Overview

Replacement Information

Key Specifications Table

CAS #	Empirical Formula
51-83-2	C₆H₁₅ClN₂O₂

Pricing & Availability

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Description
Overview	An unsubstituted carbamoyl ester that acts as an agonist for nicotinic and muscarinic acetylcholine receptors. Carbachol is totally resistant to the action of acetylcholine esterase (AChE) and non-specific cholinesterases. Inhibits apoptotic death of cultured granule neurons.
Catalogue Number	212385
Brand Family	Calbiochem®
Synonyms	Carbamoylcholine Chloride

References
References	Jence, M., et al. 1995. J. Neurochem. 64, 1605. Yan, G.M., et al. 1995. Mol. Pharmacol. 47, 248. Mangels, L.A., and Gnegy, M.E. 1992. J. Biol. Chem. 267, 5847. Watanabe, A.M., et al. 1992. In Basic and Clinical Pharmacology, Fifth Edition Katzung, B.G. ed.) Appleton and Lange, Norwalk, CT, p. 82. Howe, P.H., et al. 1986. J. Pharmacol. Exp. Ther. 239, 574.

Product Information
CAS number	51-83-2
ATP Competitive	N
Form	White fine crystalline solid
Hill Formula	C₆H₁₅ClN₂O₂
Chemical formula	C₆H₁₅ClN₂O₂
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Agonist for nicotinic and muscarinic acetylcholine receptors
Purity	≥98% by titration

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	GA0875000

Safety Information
R Phrase	R: 26/27/28-36/37/38 Very toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin.
S Phrase	S: 22-36/37/39-45 Do not breathe dust. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Highly Toxic
Hazardous Materials Attention:	Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage	+15°C to +30°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Documentation

Carbachol - CAS 51-83-2 - Calbiochem SDS

Title
Safety Data Sheet (SDS)

Carbachol - CAS 51-83-2 - Calbiochem Certificates of Analysis

Title	Lot Number
212385	Enter Lot Number

References

Reference overview
Jence, M., et al. 1995. J. Neurochem. 64, 1605. Yan, G.M., et al. 1995. Mol. Pharmacol. 47, 248. Mangels, L.A., and Gnegy, M.E. 1992. J. Biol. Chem. 267, 5847. Watanabe, A.M., et al. 1992. In Basic and Clinical Pharmacology, Fifth Edition Katzung, B.G. ed.) Appleton and Lange, Norwalk, CT, p. 82. Howe, P.H., et al. 1986. J. Pharmacol. Exp. Ther. 239, 574.

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	23-February-2023 JSW
Synonyms	Carbamoylcholine Chloride
Description	An unsubstituted carbamoyl ester that acts as an agonist for nicotinic and muscarinic acetylcholine receptors. Known to increase cytosolic Ca²⁺ and InsP₃ and decrease cAMP levels. Resistant to the action of acetylcholine esterase (AChE) and non-specific cholinesterases. Inhibits apoptotic death of cultured granule neurons.
Form	White fine crystalline solid
CAS number	51-83-2
RTECS	GA0875000
Chemical formula	C₆H₁₅ClN₂O₂
Structure formula
Purity	≥98% by titration
Solubility	H₂O (100 mg/ml), Ethanol (20 mg/ml), and Methanol(100 mg/ml)
Storage	+15°C to +30°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
Toxicity	Highly Toxic
Merck USA index	14, 1779
References	Jence, M., et al. 1995. J. Neurochem. 64, 1605. Yan, G.M., et al. 1995. Mol. Pharmacol. 47, 248. Mangels, L.A., and Gnegy, M.E. 1992. J. Biol. Chem. 267, 5847. Watanabe, A.M., et al. 1992. In Basic and Clinical Pharmacology, Fifth Edition Katzung, B.G. ed.) Appleton and Lange, Norwalk, CT, p. 82. Howe, P.H., et al. 1986. J. Pharmacol. Exp. Ther. 239, 574.