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Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
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Buffer Detection Kit for Magnetic Beads
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505894
Sigma-AldrichCGP 7930 - CAS 57717-80-3 - Calbiochem
A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB receptor. Shown to modulate GABAB receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABAB receptors. Exhibits anxiolytic effects in rodents.
Catalogue Number
505894
Brand Family
Calbiochem®
Synonyms
GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930
References
References
Adams, C. et al., 2007. CNS Drug Rev.13, 308. Pin, J.P., et al., 2007. Curr. Neuropharmacol.5, 195.
Adams, C. et al., 2007. CNS Drug Rev.13, 308. Pin, J.P., et al., 2007. Curr. Neuropharmacol.5, 195.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
20-September-2013 JSW
Synonyms
GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930
Description
A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB receptor. Shown to modulate GABAB receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABAB receptors. Exhibits anxiolytic effects in rodents.
Form
Pale yellow solid
CAS number
57717-80-3
Chemical formula
C₁₉H₃₂O₂
Structure formula
Purity
≥98% by HPLC
Solubility
DMSO (100 mM) or Ethanol (100 mM)
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Adams, C. et al., 2007. CNS Drug Rev.13, 308. Pin, J.P., et al., 2007. Curr. Neuropharmacol.5, 195.
