504595 Sigma-AldrichBcr-abl Inhibitor IV, Imatinib - CAS 220127-57-1 - Calbiochem
Synonyms: Abl Inhibitor V, PDGFR Tyrosine Kinase Inhibitor XXIV, c-Kit Inhibitor IV, 4-((4-Methyl-1-piperazinyl)methyl)-N-(4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)phenyl)benzamide, Methanesulfonate, STI571
Recommended Products
Overview
Replacement Information |
---|
Key Specifications Table
CAS # | Empirical Formula |
---|---|
220127-57-1 | C₂₉H₃₁N₇O • CH₃SO₃H |
Products
Catalog Number | Packaging | Qty/Pack | |
---|---|---|---|
5.04595.0001 | Glass bottle | 50 mg |
Product Information | |
---|---|
CAS number | 220127-57-1 |
Form | White solid |
Hill Formula | C₂₉H₃₁N₇O • CH₃SO₃H |
Hygroscopic | Hygroscopic |
Reversible | Y |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
---|
Biological Information | |
---|---|
Primary Target | Abl |
Secondary target | PDGFR, c-kit |
Purity | ≥99% by HPLC |
Physicochemical Information | |
---|---|
Cell permeable | Y |
Dimensions |
---|
Materials Information |
---|
Toxicological Information |
---|
Safety Information according to GHS |
---|
Safety Information |
---|
Product Usage Statements |
---|
Packaging Information | |
---|---|
Packaged under inert gas | Packaged under inert gas |
Transport Information |
---|
Supplemental Information |
---|
Specifications |
---|
Global Trade Item Number | |
---|---|
Catalog Number | GTIN |
5.04595.0001 | 04055977243901 |
Documentation
Bcr-abl Inhibitor IV, Imatinib - CAS 220127-57-1 - Calbiochem SDS
Title |
---|
References
Reference overview |
---|
Lin, Y.L., et al. 2013. Proc. Natl. acad. Sci. USA 110, 1664. Okada, M., et al. 2004. Blood 103, 2299. Capdeville, R., et al. 2002. Nat. Rev. Drug. Res. 1, 493. Oetzel, C., et al. 2000. Clin Cancer Res. 6, 1958. Schindler, T., et al. 2000. Science 289, 1938. Buchdunger, E., et al. 2000. J. Pharmacol. Exp. Ther. 295, 139. Carroll. M., et al. 1997. Blood 90, 4947. Zimmermann, J., et al. 1997. Bioorg. Med. Chem. Lett. 7, 187. Druker, B.J., et al. 1996. Nat. Med. 2, 561. |