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AB4340 Anti-Zscan4 Antibody

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100 µg  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWB, IF, IPRbAffinity PurifiedPolyclonal Antibody
Catalogue NumberAB4340
DescriptionAnti-Zscan4 Antibody
Alternate Names
  • Zinc finger and SCAN domain containing protein 4C
Background InformationZinc finger and SCAN domain containing protein 4, also called Zscan4, is an embryonic stem (ES) cell-specific transcription factor required to regulate pluripotency. Zscan4 binds and regulates telomere elongation in order to maintain genomic stability and acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) in undifferentiated ES cells.
Product Information
FormatAffinity Purified
  • Embryonic Stem Cell lysates
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
ApplicationAnti-Zscan4 Antibody is a highly specific rabbit polyclonal antibody, that targets Zinc Finger Protein & has been tested in western blotting, Immunofluorescence & IP.
Key Applications
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation
Application NotesImmunofluorescence Analysis: A 1:1,000 dilution from a representative lot detected Zscan4 in mouse iPS and R1 Embyonic Stem cells. Data courtesy of the Melanie Welham lab at The University of Bath, UK
Immunoprecipitation Analysis: A 1:4,000 dilution from a representative lot detected Zscan4 in cytoplasmic and nuclear extracts in IP experiments conducted by the Melanie Welham lab at The University of Bath, UK. (Data not shown)
Western Blotting Analysis: A representative lot of this antibody was used to detect Zscan4 in Wild-type (WT) and Gsk-3 double knock-out (DKO) mouse embryonic stem cells (ESCs) (Storm, M.P., et al. (2014). PLoS One. 9(3):e89821).
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to mouse Zscan4.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
Species Reactivity
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Zscan4c
  • Gm397
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~65 kDa observed. The calculated molecular weight of this protein is 57 kDa. An uncharacterized band may be observed at ~50 kDa in some cell lysates.ZSCAN4 bands may be observed at both ~72 kDa and ~40 kDa when preparing cell lysates with SDS buffer. Additionally, a ZSCAN4 doublet may be observed at ~72 kDa when using cytosolic or nuclear extracts.
Physicochemical Information
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse Embryonic Stem cell lysates.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected Zscan4 in 10 µg of Embryonic Stem cell lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Global Trade Item Number
Catalog Number GTIN
AB4340 04053252859526


Anti-Zscan4 Antibody SDS


Safety Data Sheet (SDS) 

Anti-Zscan4 Antibody Certificates of Analysis

TitleLot Number
Anti-Zscan4 3082492
Anti-Zscan4 - Q2144996 Q2144996
Anti-Zscan4 - 2520373 2520373
Anti-Zscan4 - 3200630 3200630
Anti-Zscan4 - 3385852 3385852
Anti-Zscan4 - 3690683 3690683
Anti-Zscan4 - 3807973 3807973
Anti-Zscan4 - 3905048 3905048
Anti-Zscan4 - 3924044 3924044
Anti-Zscan4 - 4005693 4005693


Reference overviewPub Med ID
Zscan4 is regulated by PI3-kinase and DNA-damaging agents and directly interacts with the transcriptional repressors LSD1 and CtBP2 in mouse embryonic stem cells.
Storm, MP; Kumpfmueller, B; Bone, HK; Buchholz, M; Sanchez Ripoll, Y; Chaudhuri, JB; Niwa, H; Tosh, D; Welham, MJ
PloS one  9  e89821  2014

Show Abstract
24594919 24594919
Role of Tet proteins in enhancer activity and telomere elongation.
Lu, F; Liu, Y; Jiang, L; Yamaguchi, S; Zhang, Y
Genes & development  28  2103-19  2014

Show Abstract
25223896 25223896